Advances in Bioscience and Biotechnology

Volume 5, Issue 6 (May 2014)

ISSN Print: 2156-8456   ISSN Online: 2156-8502

Google-based Impact Factor: 1.18  Citations  h5-index & Ranking

Development of Melanoma and Cancer without Decreasing of Cambial Cells Number in Morphofunctional Zones

HTML  XML Download Download as PDF (Size: 932KB)  PP. 493-500  
DOI: 10.4236/abb.2014.56059    3,787 Downloads   4,916 Views  Citations

ABSTRACT

In age groups from 20 to 60 years old, proliferation and differentiation of cells happen in a morphofunctional zone, in the electric field excited by 12 pairs of mother and daughter cells, turned out at cambial cells division. Thus in daughter cells the Src SH2 domain necessary both for cytoskeleton formation and tyrosinase activization is activated. If the conditions for strengthening of tyrosinase activity are created in organism, the portion of Src participating in the cytoskeleton building can decrease to critical level that will lead to development of a malignant tumor. If action of a stimulating factor is quite strong, proliferation of malignant cells begins at a stage of melanocyte, and a melanoma occurs. If action of factors is long and not strong, more remote descendants of daughter cells proliferate, and a cancer appears. In order that there will be a normal differentiation of malignantly changed daughter cells, it is necessary to block the tyrosinase. Thus all SH2 domains will go on cell cytoskeleton formation.

Share and Cite:

Yavisheva, T. and Shcherbakov, S. (2014) Development of Melanoma and Cancer without Decreasing of Cambial Cells Number in Morphofunctional Zones. Advances in Bioscience and Biotechnology, 5, 493-500. doi: 10.4236/abb.2014.56059.

Copyright © 2024 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.