Author(s)

Verónica Serrano-dela Cruz, Alicia Martínez-Varea, María José Núñez-Valera, Antonio Abad-Carrascosa, Vicente Diago, Alfredo Perales-Marín

Department of Obstetrics and Gynecology, La Fe University Hospital, University of Valencia, Valencia, Spain.

Fetoneonatal alloimmune thrombocytopenia is an infrequent and severe disease that is unexpectedly found after an uncomplicated first pregnancy. Affected infants might show unexplained purpura, intracranial hemorrhage, and/or gastrointestinal or genitourinary hemorrhage. Nevertheless, in asymptomatic newborns the thrombocytopenia may be discovered incidentally. We describe a case report that highlights that the incidental diagnosis of FNAIT allows both properly managing the newborn, and detecting maternal anti-HPA1a antibodies in order to prevent the disease in subsequent pregnancies. A non-invasive treatment based on IVIgG allowed to this patient to prevent FNAIT in her second pregnancy.

Fetoneonatal Alloimmune Thrombocytopenia; Anti-HPA1a Antibodies

Cruz, V. , Martínez-Varea, A. , Núñez-Valera, M. , Abad-Carrascosa, A. , Diago, V. and Perales-Marín, A. (2014) Neonatal Alloimmune Thrombocytopenia Due to Maternal Anti HPA1a Antibodies: Case Report and Management of Subsequent Pregnancy. Open Journal of Obstetrics and Gynecology, 4, 213-216. doi: 10.4236/ojog.2014.45035.