Journal of Biomedical Science and Engineering

Volume 6, Issue 10 (October 2013)

ISSN Print: 1937-6871   ISSN Online: 1937-688X

Google-based Impact Factor: 0.66  Citations  h5-index & Ranking

Dobesilate for dry age-related macular degeneration

HTML  Download Download as PDF (Size: 176KB)  PP. 8-14  
DOI: 10.4236/jbise.2013.610A2002    3,849 Downloads   6,175 Views  Citations

ABSTRACT

We have evaluated the effects of intravitreal dobesilate, a synthetic fibroblast growth factor inhibitor, in patients with dry age-related macular degeneration, an inflammatory-related retinal disease without available treatment up to date. 36 eyes from 36 patients with dry age-related macular degeneration were treated with a single intravitreal dobesilate injection. The end points were the improvement from baseline visual acuity and normalization of retinal histology at one month. Intravitreal dobesilate injection resulted in a significant improvement in functional and anatomical outcomes at one month after injection. Our results suggest that intravitreal dobesilate may increase the chance of visual acuity gain in dry age-related macular degeneration, even in cases with initial low vision. This study supports the findings of previously published case reports, regarding the short-term improvement in visual acuity by intravitreal dobesilate injection in different degenerative retinal diseases.

Share and Cite:

Cuevas, P. , Outeiriño, L. , Azanza, C. , Angulo, J. and Giménez-Gallego, G. (2013) Dobesilate for dry age-related macular degeneration. Journal of Biomedical Science and Engineering, 6, 8-14. doi: 10.4236/jbise.2013.610A2002.
Journals Menu
Follow SCIRP
Contact us
+1 323-425-8868
customer@scirp.org
WhatsApp +86 18163351462(WhatsApp)
Click here to send a message to me 1655362766
Paper Publishing WeChat

Copyright © 2024 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.