Author(s)

Michael Veith, Cécile Dufloux, Soraya Rasi Ghaemi, Cenk Aktas, Nicolas H. Voelcker

Department of Inorganic Chemistry, Saarland University, Saarbrücken, GermanyINM—Leibniz Institute for New Materials, CVD/Biosurfaces Group, Saarbrücken, Germany.
INM—Leibniz Institute for New Materials, CVD/Biosurfaces Group, Saarbrücken, Germany.
Mawson Institute, Division of Information Technology, Engineering and the Environment Division Office, Mawson Lakes Campus, University of South Australia, Adelaide, Australia.

By decomposing a molecular precursor we fabricated a novel surface based on an aluminium/aluminiumoxide composite incorporating nanotopography gradient to address high-throughput and fast analysis method for studying stem cell differentiation by nanostructures. Depending on the topography of the nanostructures, mesenchymal stem cells exhibit a diverse proliferation and differentiation behavior.

Gradient; Nanowires; Stem Cell;Topography

Veith, M. , Dufloux, C. , Ghaemi, S. , Aktas, C. and Voelcker, N. (2013) Gradients of Al/Al₂O₃ nanostructures for screening mesenchymal stem cell proliferation and differentiation. Open Journal of Regenerative Medicine, 2, 74-79. doi: 10.4236/ojrm.2013.23011.