Diabetic cardiomyopathy—What do we know about it? - World Journal of Cardiovascular Diseases

WJCD > Vol.3 No.5, August 2013

World Journal of Cardiovascular Diseases

Volume 3, Issue 5 (August 2013)

ISSN Print: 2164-5329 ISSN Online: 2164-5337

Google-based Impact Factor: 0.38 Citations

Diabetic cardiomyopathy—What do we know about it? ()

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Download as PDF (Size: 120KB) PP. 26-32

DOI: 10.4236/wjcd.2013.35A005 4,956 Downloads 8,309 Views Citations

Author(s)

Muhammad Asrar ul Haq, Vivek Mutha, Nima Rudd, Chiew Wong

Affiliation(s)

Department of Medicine, University of Melbourne, Melbourne, Australia Department of Cardiology, The Northern Hospital, Melbourne, Australia.

ABSTRACT

Diabetic cardiomyopathy is defined as the presence of myocardial dysfunction in patients with diabetes in the absence of coronary artery disease, hypertension, or other known cardiac disease. Diabetes has been shown to affect the heart through various cellular mechanisms leading to enhanced myocardial fibrosis, left ventricular hypertrophy, systolic and diastolic dysfunction. With increasing incidence of type II diabetes mellitus, it has continuously rising health and financial implications in both developed and developing countries. Hyperglycaemia seems to be the main deriving force, and careful glycaemic control as well as early administration of neurohormonal antagonists currently remains the mainstay of therapy. Many newer treatment targets are currently being explored. Here we present a brief review of its pathophysiology, association with heart failure symptoms, and management strategies.

KEYWORDS

Cardiomyopathy; Diabetes; Heart Failure

Share and Cite:

Asrar ul Haq, M. , Mutha, V. , Rudd, N. and Wong, C. (2013) Diabetic cardiomyopathy—What do we know about it?. World Journal of Cardiovascular Diseases, 3, 26-32. doi: 10.4236/wjcd.2013.35A005.

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