Field evaluation of KO-Tab 1-2-3® long lasting insecticidal net performance in Milenge, Zambia - Journal of Biomedical Science and Engineering

JBiSE > Vol.6 No.7, July 2013

Journal of Biomedical Science and Engineering

Volume 6, Issue 7 (July 2013)

ISSN Print: 1937-6871 ISSN Online: 1937-688X

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Field evaluation of KO-Tab 1-2-3^® long lasting insecticidal net performance in Milenge, Zambia ()

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DOI: 10.4236/jbise.2013.67A1002 2,709 Downloads 4,344 Views Citations

Author(s)

Emmanuel Chanda, Alister Kandyata, Javan Chanda, Pascalina Chanda-Kapata

Affiliation(s)

Ministry of Health, National Malaria Control Centre, Lusaka, Zambia.
Ministry of Health, National Malaria Control Centre, Lusaka, Zambia Department of Biomedical Sciences, School of Medicine, University of Zambia, Lusaka, Zambia.
Ministry of Health, National Malaria Control Centre, Lusaka, Zambia；Department of Biological Sciences, School of Natural Sciences, University of Zambia, Lusaka, Zambia.
Ministry of Health, Ndeke House, Lusaka, Zambia.

ABSTRACT

Insecticide treated nets (ITNs) play a pivotal role in the prevention and control of malaria. Conversely, inadequate levels of ownership, utilization and durability invariably compromise their efficacy. Operational performance of the KO-Tab 1-2-3

Long Lasting Insecticidal Nets (LLINs) was assessed using the World Health Organization (WHO) standard entomological and epidemiological procedures, and a pretested structured questionnaire. The median knock down time for Anopheles funestus s.l. was 30 minutes (95% CI 26.3 - 34.0). Post exposure mean mortality rates were 34% at one hour and 80.0% at 24 hours (OR = 0.13, P = 0.00002). Children between the ages of 1 - 4 years old exhibited higher false positives as compared to the 5 - 15 years age groups (OR = 0.10, P = 0.0006). Parasite prevalence varied between rapid diagnostic tests (RDTs) (40.4%) and microscopy (31.3%) (OR = 0.67, P = 0.2825) with 9.2% discordant RDT false positives. All malaria positive children were Plasmodium falciparum mono-infections. Hospital admissions reduced by 28% between 2005 and 2008, with case fatality rates reducing by 19% between 2006 and2007 inchildren under five years. No marked heterogeneity between LLINs ownership (66%) and utilization (48.3%) was observed (OR = 0.49, P = 0.0978). There was complete (100%) community level knowledge of KO-Tab 1-2-3

LLINs. The study provides evidence of potential of KO-Tab 1-2-3

LLINs for operational scale distribution, and substantiates the need for further longitudinal studies to monitor their insecticidal and physical durability.

KEYWORDS

Long Lasting Insecticidal Nets; Malaria Vector Control; Field Evaluation; Zambia

Share and Cite:

Chanda, E. , Kandyata, A. , Chanda, J. and Chanda-Kapata, P. (2013) Field evaluation of KO-Tab 1-2-3^® long lasting insecticidal net performance in Milenge, Zambia. Journal of Biomedical Science and Engineering, 6, 4-10. doi: 10.4236/jbise.2013.67A1002.

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