Advances in Chemical Engineering and Science

Volume 3, Issue 3 (July 2013)

ISSN Print: 2160-0392   ISSN Online: 2160-0406

Google-based Impact Factor: 1.41  Citations  h5-index & Ranking

Process for the Obtention of Coumaric Acid from Coumarin: Analysis of the Reaction Conditions

HTML  Download Download as PDF (Size: 1280KB)  PP. 195-201  
DOI: 10.4236/aces.2013.33025    8,777 Downloads   13,898 Views  Citations

ABSTRACT

Coumaric acid can be obtained from basic hydrolysis of coumarin, through a reaction process consisting on opening the lactone ring and cis-trans isomerization. Parameters such as reaction time, temperature, NaOH concentration, solvent and reaction atmosphere, have been thoroughly studied and analyzed, in order to determine the appropriate conditions for the maximum conversion efficiency of coumarin into coumaric acid. Experimental results show that the best conditions are a 1 hour reaction time, at 160℃, with a 20% sodium hydroxide aqueous solution, and in an inert reaction atmosphere.

Share and Cite:

N. López-Castillo, A. Rojas-Rodríguez, B. Porta and M. Cruz-Gómez, "Process for the Obtention of Coumaric Acid from Coumarin: Analysis of the Reaction Conditions," Advances in Chemical Engineering and Science, Vol. 3 No. 3, 2013, pp. 195-201. doi: 10.4236/aces.2013.33025.

Cited by

[1] A reversible turn-on fluorescent probe for quantitative imaging and dynamic monitoring of cellular glutathione
Analytica Chimica Acta, 2022
[2] Computer-Aided Design and Synthesis of (Functionalized quinazoline)–(α-substituted coumarin)–arylsulfonate Conjugates against Chikungunya Virus
International journal of …, 2022
[3] Coumarins from red delicious apple seeds: Extraction, phytochemical analysis, and evaluation as antimicrobial agents
2020
[4] Phytochemical, antioxidant and antitumor studies of coumarins extracted from granny smith apple seeds by different methods
2020
[5] Preliminary phytochemical characterization of extracts of the orchid Epidendrum coryophorum
2020
[6] Synthesis of 6-and 7-alkoxy-4-methylcoumarins from corresponding hydroxy coumarins and their conversion into 6-and 7-alkoxy-4-formylcoumarin derivatives
2020
[7] An Enzymatic Method to Remove Toxic Coumarin from Cinnamon.
2020
[8] Coumarins from Creston Apple Seeds: Isolation, Chemical Modification, and Cytotoxicity Study
J App Pharm Sci, 2018
[9] Photorheological Ionic Liquids
The Journal of Physical Chemistry B, 2015
[10] Synthesis of novel coumarin derivatives based on 6-aminocoumarin, kinetic inspection of base hydrolysis, and spectrophotometric tracer of intermediate progress
Monatshefte für Chemie-Chemical Monthly, 2015
[11] Coumarins: auspicious cholinesterase and monoamine oxidase inhibitors
Current topics in medicinal chemistry, 2015
[12] Sulfated phenolic acids as readily activatable storage forms of antifouling agents in marine plants
Dissertation, 2015
[13] Synthesis of alkyl coumarate esters by celite-bound lipase of Bacillus licheniformis SCD11501
Journal of Molecular Catalysis B: Enzymatic, 2014
[14] Organic Solvent Tolerant Lipases and Applications
The Scientific World Journal, 2014
[15] Synthesis of alkyl coumarate esters by celite-bound lipase of Bacillus licheniformis SCD11501
Journal of Molecular Catalysis B: Enzymatic, 2014
[16] Bioinspired copper catalyst effective for both reduction and evolution of oxygen
Nature communications, 2014
[17] Photochemical control of rheology
2014
[18] Novel coumarins isolated from the seeds of Citrullus lanatus as potential antimicrobial agents
[19] Antibacterial and Antitumor Potentials of Some Novel Coumarins

Journals Menu
Follow SCIRP
Contact us
+1 323-425-8868
customer@scirp.org
WhatsApp +86 18163351462(WhatsApp)
Click here to send a message to me 1655362766
Paper Publishing WeChat

Copyright © 2024 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.