Primary Anaplastic Large Cell Lymphoma of the Nasal Cavity: A Case Report ()
ABSTRACT
Introduction: Anaplastic large-cell lymphoma occurring in the nasal cavity is a rare disease. The latest World Health
Organization (WHO) Classification recognizes three
distinct subtypes: primary systemic anaplastic lymphoma kinase positive been our case, primary systemic anaplastic
lymphoma kinase negative and primary cutaneous types. Through this case study, we focus on the clinical
presentation, treatment and prognostic characteristics of this pathology.Case Presentation: We report the case of a patient aged 32 years, who
presented for seven months a runny nose associated with swelling of the face on
the left side, without peripheral lymphadenopathy or general signs. A Blondeau scanner objectified a total filling of the
frontal and left maxillary sinus, and a filling of the left nasal cavity.
Complete resection of the tumor was performed. Histological examination was in
favor of anaplastic large T-cell lymphoma anaplastic
lymphoma kinase positive. The patient was stage IE according to Ann Arbor classification, with an International Prognostic Index estimated at one. Thus, the patient received six cycles of CHOP
chemotherapy. Currently, he is in good loco-regional control with a decline of
three months.Conclusion: The rarity of this case lies partly in the lymphomatous localization in the nasal cavity, and secondly in the anaplastic histology. It poses a diagnostic problem. So, we conclude that in
case of any symptom of nasal cavities, it is necessary to explore and possibly
biopsy if tumor, before surgery, because lymphomas are chemosensitive disease.
Share and Cite:
I. Ouafki, T. Sghiri, S. Boutayeb, M. Mouanis, M. Maher, H. Mrabti and H. Errihani, "Primary Anaplastic Large Cell Lymphoma of the Nasal Cavity: A Case Report,"
International Journal of Clinical Medicine, Vol. 4 No. 4, 2013, pp. 195-199. doi:
10.4236/ijcm.2013.44034.