Author(s)

Rajesh R. Tampi, Banu Ozkan, Deena Williamson

Department of Psychiatry, University of Maryland, Baltimore, USA.
Department of Psychiatry, Yale University School of Medicine, New Haven, USA.
Saint Francis Hospital and Medical Center, Hartford, USA.

Objective: To examine the efficacy of gabapentin for the treatment of behavioral and psychological symptoms of dementia (BPSD). Design: A retrospective chart review. Settings: Tertiary care geriatric psychiatry inpatient unit. Participants: 230 patients with BPSD. Measurements: The socio-demographic information, type of behaviors, co-morbid psychiatric and medical diagnoses, daily doses of medications and side-effects were recorded. Results: Of the 230 patients, 22 were treated with gabapentin. Twenty of these patients were on a combination of gabapentin and an antipsychotic medication while two patients were treated with gabapentin monotherapy. Eighteen of the 20 patients in the combination group tolerated the treatments with little or no side effects as did the two patients in the monotherapy group. Conclusions: Gabapentin may be a safe option for the treatment of BPSD in combination with antipsychotic medications. Gabapentin may also be effective as monotherapy in certain patients with BPSD.

Behavioral and Psychological Symptoms of Dementia; Neuropsychiatric Symptoms of Dementia; Anticonvulsants; Gabapentin

Tampi, R., Ozkan, B. and Williamson, D. (2012) Gabapentin for the treatment of behavioral and psychological symptoms of dementia. Advances in Alzheimer's Disease, 1, 13-16. doi: 10.4236/aad.2012.12002.