DABCO Promoted an Efficient and Convenient Synthesis of Pyrrole in Aqueous Medium - International Journal of Organic Chemistry

IJOC > Vol.2 No.2, June 2012

International Journal of Organic Chemistry

Volume 2, Issue 2 (June 2012)

ISSN Print: 2161-4687 ISSN Online: 2161-4695

Google-based Impact Factor: 1.26 Citations

DABCO Promoted an Efficient and Convenient Synthesis of Pyrrole in Aqueous Medium ()

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Download as PDF (Size: 188KB) PP. 159-165

DOI: 10.4236/ijoc.2012.22024 7,038 Downloads 13,718 Views Citations

Author(s)

Harshadas Mitaram Meshram, Vikas Madhukar Bangade, Bandi Chennakesava Reddy, Gudimella Santosh Kumar, Pramod Bhagwan Thakur

Affiliation(s)

Discovery Laboratory, Organic Chemistry Division—I, Indian Institute of Chemical Technology, Hyderabad, India.

ABSTRACT

The synthesis of C-substituted and N-substituted pyrrole is described by the reaction of phenacyl bromides, pentane-2, 4-dione and amine in aqueous medium using DABCO as a catalyst. The method is very convenient and applicable for alkyl as well as aryl amines and phenacyl bromides. The procedure is amenable for the synthesis of new substituted pyrroles. Moreover, aqueous medium makes the method more eco-friendly.

KEYWORDS

Phenacyl Bromide; Pentane-2, 4-dione; Amines; DABCO; Water; Pyrroles

Share and Cite:

Meshram, H. , Bangade, V. , Reddy, B. , Kumar, G. and Thakur, P. (2012) DABCO Promoted an Efficient and Convenient Synthesis of Pyrrole in Aqueous Medium. International Journal of Organic Chemistry, 2, 159-165. doi: 10.4236/ijoc.2012.22024.

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