Author(s)

Malalaniaina Andrianarison¹, Malala Razakanaivo², Rindra Rafanomezantsoa³, Mendrika Fifaliana Rakotoarisaona¹, Odilon Laza⁴, Fandresena Arilala Sendrasoa⁵, Irina Mamisoa Ranaivo⁶, Léa Raobela³, Lala Soavina Ramarozatovo⁷, Fahafahantsoa Rapelanoro Rabenja⁵

¹Unit of Dermatology, University Hospital Center of Public Health and Care Analakely, Antananarivo, Madagascar.
²Unit of Radiotherapy, University Hospital Center Joseph Ravoahangy Andrianavalona, Antananarivo, Madagascar.
³Unit of Ophthalmology, University Hospital Center Joseph Ravoahangy Andrianavalona, Antananarivo, Madagascar.
⁴Unit of Pathology, University Hospital Center Tambohobe, Fianarantsoa, Madagascar.
⁵Unit of Dermatology, University Hospital Center of Joseph Raseta Befelatanana, Antananarivo, Madagascar.
⁶Unit of Dermatology, University Hospital Center Morafeno, Toamasina, Madagascar.
⁷Unit of Dermatology and Internal Medicine, University Hospital Center of Joseph Raseta Befelatanana, Antananarivo, Madagascar.

Introduction: Kaposi sarcoma disease is a proliferative and multifocal disorder with dual components, vascular and fibroblastic cellular, cutaneous and visceral expression. Kaposi Sarcoma can affect the ocular surface and adnexa and can masquerade as other entities, delaying prompt diagnosis can lead to diagnostic wandering delaying treatment. Our aim is to describe a case of KS of the eyelid in an HIV seronegative patient. Case Presentation: A seventy-year-old man developed a bilateral growing tumoral reddish purple vascular mass on both the lower and upper eyelid involving rapidly for 6 months. Both feet and the two shanks show the presence of a brown-violet tumor-shaped formation. The patient was negative for HIV. Histology examination showed a nodular tumor-like mass with a fibro hemangioma-epitheliomatous. Polymerase chain reaction was positive for human herpes virus 8. Initial chemotherapy followed by surgery was proposed to the patient. Unfortunately, the patient rejected treatment and was lost to follow-up. Conclusion: This case reports the difficulty of managing KS in developing countries.

Eyelid, HHV-8, Interferon, Kaposi Sarcoma

Andrianarison, M. , Razakanaivo, M. , Rafanomezantsoa, R. , Rakotoarisaona, M. , Laza, O. , Sendrasoa, F. , Ranaivo, I. , Raobela, L. , Ramarozatovo, L. and Rabenja, F. (2024) Eyelid Kaposi Sarcoma in HIV-Negative Patient. Journal of Cancer Therapy, 15, 92-97. doi: 10.4236/jct.2024.153010.