Author(s)

Mushera Aganze Alain^1,2*, Raha Maroyi Kenny^1,2, Kakisingi Mibi De Joseph^1,2, Musese Nguru Marie Constance^1,2, Julien Bwama Botalatala^1,2, Mbozi Andrea^1,2, Koko Kasengire Euphrasie³, Imani Erahamoba Pince⁴, Olivier Nyakio^1,2,5

¹Department of Gynecology and Obstetrics, Panzi General Referral Hospital, Bukavu, Democratic Republic of the Congo.
²Department of Medicine and Public Health, Evangelical University in Africa, Bukavu, Democratic Republic of the Congo.
³Biopharm Hospital, Bukavu, Democratic Republic of the Congo.
⁴International Institute of Tropical Agriculture, IITA Olusegun Obasanjo Campus, Kalambo Station, South Kivu, Democratic Republic of the Congo.
⁵School of Medicine, Official University of Bukavu, Bukavu, Democratic Republic of the Congo.

Hypertensive disorders of pregnancy are among the leading causes of severe maternal morbidity and mortality, particularly in developing countries. Hypertensive disorders of pregnancy are among the leading causes of severe maternal morbidity and mortality, particularly in developing countries, maternal hypocalcaemia being a factor favouring the onset of arterial hypertension during pregnancy. The aim was to determine the maternal and perinatal prognosis of patients with hypertensive disorders of pregnancy as a function of serum ionised calcium levels. Material and Methods: A cross-sectional analytical study of 114 patients with arterial hypertension during pregnancy or during pregnancy or in the postpartum period at the HGR/Panzi from 1 January 2021 to 30 June 2022, text was entered using Microsoft Office Word 2010 and the tables were analysed using Excel 2010. The data was analysed using SPSS version 20.0 and Stata 14.0. The associations of the variables were calculated using Pearson's chi-square test, with a significance threshold set at a value of p < 0.05. Study of risk factors, Odds ratios and their confidence intervals were estimated in a univariate analysis. The most determining factors were identified by multivariate analysis using the Forward conditional logistic regression model. Results: The mean gestational age was 34.43 ± 4.327 amenorheas weeks, 46.6% of patients had a vaginal delivery, 66.65% of which were indicated for maternal prognosis, maternal complications were associated with maternal hypocalcaemia in 81, 82% (P = 0.043) and an OR = 3.255 (P = 0.0158) threefold risk that the patient presenting with a complication is likely to be in a state of hypocalcaemia at 95% confidence index, and fetal prognosis was not significantly related to maternal calcaemia. Conclusion: Maternal hypocalcaemia is one of the factors that can influence maternal-foetal complications maternal-fetal complications, early management and prevention of this pathology is pathology is important to reduce maternal-fetal morbidity and mortality.

Hypocalcaemia, Arterial Hypertension During Pregnancy and Maternal and Perinatal Prognosis

Alain, M. , Kenny, R. , Joseph, K. , Constance, M. , Botalatala, J. , Andrea, M. , Euphrasie, K. , Pince, I. and Nyakio, O. (2024) Serum Calcium Ionised Rate and Materno-Perinatal Prognosis in Arterial Hypertension in Pregnancy at the Reference General Hospital of Panzi. Open Journal of Obstetrics and Gynecology, 14, 422-434. doi: 10.4236/ojog.2024.143037.