Author(s)

Prudence Ada Assoumou^1*, Davy Alex Mouinga Abayi², Yoan Mboussou³, Annick Kougou Ntoutoume⁴, Helene Nyinko Aboughe⁴, Olive Matsanga⁴, Tatiana Harly Mba Aki⁴, Emmanuel Mve Mengome²

¹Owendo University Hospital Center, Department of Surgery at the Faculty of Medicine of the University of Health Sciences, Libreville, Gabon.
²Omar Bongo Ondimba Military Instructions Hospital, Department of Surgery at the Faculty of Medicine of the University of Health Sciences, Libreville, Gabon.
³Médivision Clinic, Libreville, Gabon.
⁴Jeanne Ebori Foundation Mother and Child University Hospital Center, Department of Surgery at the Faculty of Medicine of the University of Health Sciences, Libreville, Gabon.

Introduction: Leukocoria, a whitish pupillary reflection, is a common warning sign of various pediatric ocular pathologies, including Persistent hyperplastic primary vitreous (PHVP). This case report describes the observation of a 3-year-old child with melanoderma, presenting with a white spot in the left eye since birth. Observation: Uncorrected distance visual acuity was 2/10 in the right eye and hand movements were perceived at 2 meters in the left eye. Examination of the anterior segment in the left eye revealed leukocoria and microphthalmia. The fundus examination was normal in the right eye but revealed a white mass extending from the center of the optic disc towards the temporal region in the left eye. Ocular imaging, including ocular ultrasound and optical coherence tomography, confirmed the diagnosis of PHVP, illustrated by a residual white mass at the center of the optic disc in the left eye. Conclusion: PHVP should be considered in the presence of leukocoria in a child, with urgent exclusion of retinoblastoma. This observation underscores the importance of early diagnosis for appropriate management.

PHVP, Leukocoria, Amblyopia, Ocular Imaging, Childhood

Ada Assoumou, P. , Alex Mouinga Abayi, D. , Mboussou, Y. , Kougou Ntoutoume, A. , Nyinko Aboughe, H. , Matsanga, O. , Harly Mba Aki, T. and Mve Mengome, E. (2024) A Rare Cause of Leukocoria in Children: Persistent Hyperplastic Primary Vitreous. Open Journal of Ophthalmology, 14, 63-68. doi: 10.4236/ojoph.2024.141006.