Author(s)

Fabienne Marie Soudre^1,2*, Arnaud Kouraogo^3,4, Alice Kiba^1,5, Ollo Da^3,4, Mahutin Benoîte Hounhoui⁶, Diema Nadia Karama⁶, Seraphine Mano⁶, Denis Claude Drabo², Augustin Kyetega², Raoul Karfo^1,7, Elie Kabre^1,8, Jean Sakande^1,7

¹Health Sciences Training and Research Unit, Joseph Ki-Zerbo University, Ouagadougou, Burkina Faso.
²Charles de Gaulle Pediatric University Hospital, Ouagadougou, Burkina Faso.
³Health Sciences Institute, Nazi BONI University, Bobo Dioulasso, Burkina Faso.
⁴Biochemistry Unit, Sourou Sanou University Hospital, Bobo Dioulasso, Burkina Faso.
⁵Tengandogo University Hospital, Ouagadougou, Burkina Faso.
⁶Faculty of Health Sciences, Saint Thomas d’Aquin University, Ouagadougou, Burkina Faso.
⁷Yalgado Ouedraogo University Hospital, Ouagadougou, Burkina Faso.
⁸National Agency for Environmental, Food, Labor and Health Product Safety, Ouagadougou, Burkina Faso.

Introduction: Cardiovascular disease represents a major public health burden worldwide. Research and management of risk factors contribute to the prevention of these diseases. The aim of this study was to assess the prevalence of dyslipidemia in the biochemistry unit of the Charles De Gaulle Pediatric University Hospital (CHUP-CDG) in Ouagadougou. Material and Methods: This was a descriptive and analytical cross-sectional study, with retrospective data collection from January 1, 2020 to December 31, 2022. Patients of all ages who performed a lipid panel in the CHUP-CDG biochemistry unit during the study period have been included. Results: A total of 2872 patients have been included. The mean age of the study population was 27.72 ± 19.51 years and the M/F sex ratio was 0.81. Among the patients, 22.84% had at least one dyslipidemia. The prevalences of hypercholesterolemia, hypo-HDL cholesterolemia and hyper-LDL cholesterolemia were 11.57%, 49.19% and 57.50% respectively. Hypertriglyceridemia and mixed hyperlipidemia were present in 9.04% and 2.08% of patients. Hypercholesterolemia was significantly more frequent in the female sex (p = 0.0077); hyper-LDL cholesterolemia (p = 0.0255) and mixed hyperlipidemia (p < 0.00001) in patients over 45 years of age. Conclusion: The relatively high prevalence of dyslipidemia in the study indicates a worrying situation. It would therefore appear essential to extend the search for risk factors nationwide, particularly those that can be modified, in order to reduce morbidity and mortality linked to cardiovascular disease.

Dyslipidemia, Lipid Profile, Lipid Abnormalities, Prevalence, Burkina Faso

Soudre, F. , Kouraogo, A. , Kiba, A. , Da, O. , Hounhoui, M. , Karama, D. , Mano, S. , Drabo, D. , Kyetega, A. , Karfo, R. , Kabre, E. and Sakande, J. (2024) Prevalence of Dyslipidemia among Patients Received at the Biochemistry Unit of the Charles de Gaulle Pediatric University Hospital in Ouagadougou. Advances in Biological Chemistry, 14, 16-26. doi: 10.4236/abc.2024.141002.