Author(s)

Mamadou Dian Mamoudou Diallo^1,2,3, Mamadou Mansour Diallo², Mamadou Chérif Diallo^2,3, Alpha Mamadou Diallo², Kadija Dieng^2,3, Mody Abdoulaye Barry^2,3, Mamadou Alpha Diallo^2,3, Kadidiatou Bah^2,3, Abdou Mazid Diallo³, El’hadj Zainoul Bah^2,3, Mamadou Malal Bori Diallo⁴, Mamadou Sanou Sylla⁴, Amadou Kaké^2,3

¹Diabetes Unit, Labe Regional Hospital, Labe, Guinea.
²Faculty of Health Sciences and Technology, University of Conakry, Conakry, Guinea.
³Department of Diabetes and Endocrinology, Donka Hospital and University Center, Conakry, Guinea.
⁴Neonatology Unit, Labe Regional Hospital, Labe, Guinea.

Macrosomia is defined as a term birth weight greater than or equal to 4000 grams, or greater than the 90 percentile of intrauterine growth curves. Excessive weight has harmful consequences for the newborn and is a major health concern. Objectives: To determine the frequency of neonatal macrosomia, describe risk factors and neonatal and maternal complications. Materials and methods: This was a cross-sectional study carried out between January and December 2022, involving newborns whose birth weight was greater than or equal to 4000 grams admitted to the neonatology unit of the Labe regional hospital. Results: 591 deliveries were recorded, 15 of which were macrosomic, representing a frequency of 2.54%. The average age of the women was 30.26 years. History of fetal macrosomia and diabetes was 93.33 and 71.43% respectively. The mean gestational age was 38.71 ± 0.75 SA, the mean antenatal consultation was 3 ± 0.8 and the mode of delivery was caesarean section (66.67%). Third-trimester ultrasound was performed in 53.33% of cases. Macrosomic newborns were male in 80% of cases. Neonatal complications were asphyxia (60%), hypoglycemia (20%) and hypocalcemia (13.33%). Factors associated with neonatal macrosomia were diabetes (P < 0.001), history of macrosomia (P < 0.001) and maternal obesity (P < 0.001). Conclusion: this study shows that the frequency of neonatal macrosomia is 2.54% with high neonatal morbidity among newborns hospitalized in the neonatology unit of the Labé regional hospital. Screening for macrosomia risk factors during pregnancy is essential to prevent perinatal complications.

Frequency, Macrosomia, Labe

Diallo, M. , Diallo, M. , Diallo, M. , Diallo, A. , Dieng, K. , Barry, M. , Diallo, M. , Bah, K. , Diallo, A. , Bah, E. , Diallo, M. , Sylla, M. and Kaké, A. (2024) Frequency and Risk Factors of Neonatal Macrosomia at Labe Regional Hospital in Guinea. Open Journal of Endocrine and Metabolic Diseases, 14, 26-32. doi: 10.4236/ojemd.2024.142004.