Author(s)

Fan Yang^1,2,3, Xiaoping Tan^1,2,3*

¹Department of Gastrosenterology, First Hospital of Yangtze University, Jingzhou, China.
²Digestive Disease Research Institution of Yangtze University, Jingzhou, China.
³Clinical Medical College, Yangtze University, Jingzhou, China.

In recent years, the progress of NAFLD has become an important health problem, and the prevention or delay of progress in NAFLD is a major key point. Whether or not to combine T2MD, people are interested in the mechanisms and efficacy of SGLT2i for NAFLD. In this review, we summarized the current clinical research on SGLT2i for the combination of T2MD’s NAFLD patients, and the latest evidence of external or animal experiments. These evidences will help us to more accurately understand the protective effects of SGLT2i in NAFLD. Lifestyle changes are still essential to prevent and treat NAFLD, and for all kinds of drugs that treat NAFLD in clinical trials, SGLT2i may be one of the promising treatments.

Sodium-Glucose Cotransporter-2 Inhibitors, Non-Alcoholic Fatty Liver Disease, Diabetes Mellitus

Yang, F. and Tan, X. (2024) Progress in the Study of the Hepatoprotective Effect of SGLT2i on NAFLD Patients with T2DM. Journal of Biosciences and Medicines, 12, 115-125. doi: 10.4236/jbm.2024.121011.