Author(s)

Alya Al-Furaydi, Noorah Saleh Al-Sowayan^*

Department of Biology, College of Science, Qassim University, Buraydah, Saudi Arabia.

Alzheimer’s, characterized by β-amyloid accumulation and tau hyperphosphorylation, is linked to inflammation, oxidative stress, and microglial activation, suggesting potential protective strategies. Studies have shown that natural polyphenolic anthocyanin components found in berries, such as cyanidin, can inhibit amyloid filament formation and modulate Alzheimer’s disease are polyphenolic flavonoids, which are responsible for red, purple, and blue colors in various fruits, such as red cabbage and most berries. Here, we reviewed the protective effects of anthocyanins. It has anti-inflammatory and antioxidant properties, reduces NF-κB, and affects inflammatory signaling pathways. They also improve cognitive function, making them a potential protective strategy against AD.

Anthocyanins, Oxidative Stress, Microglia Activation, NF-<1>κB

Al-Furaydi, A. and Al-Sowayan, N. (2023) Protective Effect of an Anthocyanin on Alzheimer’s Disease. Advances in Bioscience and Biotechnology, 14, 505-513. doi: 10.4236/abb.2023.1412035.