Author(s)

Coovi Nonwanou Ignace Tokpanoude^1,2*, Séraphin Ahoui³, Damien Barikissou Georgia¹, Elvire S. E. Djossou¹, Sayo Djibo¹, Gottfried Agballa¹, Ireti Nethania Elie Ataigba^4,5, Ismaël Landry Paraiso³, Omer Adjibode³, Benoit S. Agossoukpe³, Rodrigue S. Kakpo-Zannou¹, Badirou Aguemon¹

¹Unité de Santé Publique de la Faculté des Sciences de la Santé (FSS), Université d’Abomey-Calavi (UAC), Cotonou, Bénin.
²Association des Médecins Communautaires du Bénin (AMCB), Parakou, Bénin.
³Service de Néphrologie, Centre Hospitalier Universitaire Départemental du Borgou Alibori (CHUD/B-A), Parakou, Bénin.
⁴Faculté de Médecine (FMP), Institut de Formation en Soins Infirmiers et Obstétricaux (IFSIO), Parakou, Bénin.
⁵Service de Psychiatrie, Centre Hospitalier Universitaire Départemental du Borgou Alibori (CHUD/B-A), Parakou, Bénin.

Introduction: Therapeutic compliance in chronic kidney disease (CKD) represents a major challenge for the prevention of this condition, which is both a non-communicable disease (NCD) and a complication of other NCDs. Non-adherence to treatment (NOT) is a factor in the poor prognosis of CKD in developing countries, particularly in Benin. The aim of this study was to evaluate therapeutic compliance (TC) and determine the factors associated with non-compliance in patients with chronic kidney disease undergoing treatment at the Departmental University Hospital of Borgou and Alibori in Parakou (CHUD/B-A). Patients and Methods: This study was carried out in the Nephrology Department of CHUD/B-A. It was a cross-sectional, descriptive study with analytical aims that ran from December 25, 2022 to March 15, 2023 and covered data from 2017 to 2022. It involved 345 patient records meeting the diagnosis of CKD according to the KDIGO 2012 criteria. NOT was defined by a Girerd score evaluation greater than or equal to 3. Data processing and analysis were performed with R software version 4.3.0. Results: The mean age (SD) of patients was 50 years (±14.9). The prevalence of NOT was 57.1%. Potential predictors of non-adherence were: monthly revenue (p = 0.009), mode of admission (p = 0.001), phytotherapy (p = 0.040), traditional treatment (p = 0.049) and quantity of drugs (p = 0.042). Conclusion: Therapeutic compliance among chronic kidney patients still needs to be improved through awareness-raising sessions.

Chronic Kidney Disease, Therapeutic Non-Adherence, Girerd Assessment, Chronic Renal Failure, Benin

Tokpanoude, C. , Ahoui, S. , Georgia, D. , Djossou, E. , Djibo, S. , Agballa, G. , Ataigba, I. , Paraiso, I. , Adjibode, O. , Agossoukpe, B. , Kakpo-Zannou, R. and Aguemon, B. (2023) Factors Associated with Non-Compliance among Patients with Chronic Kidney Disease at the Departmental University Hospital of Borgou and Alibori in Parakou (Benin). Open Journal of Nephrology, 13, 420-434. doi: 10.4236/ojneph.2023.134039.