Author(s)

Louise Mouangue-Mbonjo^1,2*, Djibril Samaké³, Emmanuel Nchinda Choffor⁴, Esthelle Geneviève Stéphanie Minka Ngom², Florent Dimitri Badang², Ahmadou Njifou Njimah², Louis Richard Ndjock², Olive Nicole Ngaba Mballa Mambo Pouka¹

¹Otorhinolaryngology and Cervico-Maxillo-Facial Surgery Unit of Central Hospital of Yaounde, Yaounde, Cameroon.
²Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon.
³ENT and Head and Neck Surgery Department, CHU Mother-Child “Luxembourg”, Bamako, Mali.
⁴Department of Surgery and Specialties, Faculty of Health Sciences, University of Buea, Buea, Cameroon.

Background: A diverse range of pathologies affect the sinonasal cavities, because of the nonspecific nature of the symptoms, most patients with sinonasal masses are diagnosed late when the disease is at an advanced stage. The diagnostic challenge of identifying the nature of sinonasal masses before treatment would guide therapeutic strategies. Our objective was to evaluate the accuracy of computed tomography in the preoperative diagnosis of sinus masses at the Central Hospital of Yaoundé. Method: A retrospective chart review was conducted; CT scan reports and pathology reports of patients operated for sinonasal masses between January 2012 and November 2022 were compared. Results: Forty-five patients met the inclusion criteria for the study. The average age was 39.98 ± 18.34 years, with extremes of 15 and 87 years. The sex ratio H/F is 0.76 with a female predominance. The median time to consultation was 14 [12 - 18] months, with extremes of 11 and 36 months. The most frequently encountered histological type was benign tumors with sinonasal polyposis (PNS) in the lead, i.e. 34.1% of cases. The types adenocarcinoma, adenoid cystic carcinoma and non-Hodgkin’s lymphoma were represented equally in 6.8% of cases. Management was dominated by Caldwell-Luc surgery, i.e. 59.1% of cases. The frequency of disease recurrence after surgical treatment was 18.2%. As for the mortality rate, it was 11.4%. The concordance rate of the character of malignancy on imaging compared to histology was 90.9%. This level of concordance was statistically significant according to the Gamma test (p < 0.001). The diagnostic performances of imaging in malignant tumors are: Sensitivity 88.9%, Specificity 92.3%, Positive Predictive Value 88.9%, Negative Predictive Value 92.3%. This study shows that computed tomography allows the diagnosis of benign and malignant lesions of sinonasal masses but there are false positive, particularly in the case of the histological type Inverted Papilloma. Conclusion: Preoperative CT scans correlate with histology and have a prognostic role in surgically treated sinonasal masses.

Computed Tomography, Histology, Sinonasal Tumors

Mouangue-Mbonjo, L. , Samaké, D. , Choffor, E. , Ngom, E. , Badang, F. , Njimah, A. , Ndjock, L. and Pouka, O. (2023) Correlation between Computed Tomography and Histopathology Findings of Sinonasal Tumors. International Journal of Otolaryngology and Head & Neck Surgery, 12, 347-357. doi: 10.4236/ijohns.2023.125037.