Author(s)

Kamel El-Reshaid^1*, Shaikha Al-Bader², Abdullatif Al-Terki³

¹Department of Medicine, Faculty of Medicine, Kuwait University, Kuwait City, Kuwait.
²Department of Medicine, Nephrology Unit, Amiri Hospital, Ministry of Health, Kuwait City, Kuwait.
³Department of Surgery, Urology Unit, Amiri Hospital, Ministry of Health, Kuwait City, Kuwait.

Background: Gestational formation of new urolithiasis is rare yet the impact of inappropriate gestational calcium and vitamin D supplementation (Ca/DS) is underestimated. Patients and Methods: we retrospectively evaluated 75 pregnant women with history of UL, yet were stable for >2 years on dietary restrictions, for new UL after Ca/DS. Results: During the past 5 years 21 (48%) of those who had received Ca/DS had developed UL and all had high Vitamin D with hypercalcemia while the remaining 31 patients, without Ca/DS, did not have UL and maintained normal vitamin D urinary calcium without need for supplementation. Overt UL was evident by 30th weeks of gestations and most were diagnosed by ultrasonography and managed by medical expulsive therapy. Conclusion: in patients with history of UL, prudent use of Ca/DS is indicated to avoid new UL.

Calcium, Kidney, Pregnancy, Stones, Urolithiasis, Vitamin D

El-Reshaid, K. , Al-Bader, S. and Al-Terki, A. (2023) The Deleterious Effect of Inappropriate Calcium and Vitamin D Supplementation during Pregnancy in Women Predisposed to Calcium Oxalate Urolithiasis. Open Journal of Nephrology, 13, 256-262. doi: 10.4236/ojneph.2023.133025.