Author(s)

Billy Paul Kaishusha Mupendwa^1*, Espoir Batumike Murhi², Guy Mulumeoderhwa Mulinganya², Mannix Masimango Imani², Kesner Mateso², Salama Kaishusha David², Justin-Leonard Kadima Ntokamunda³, Elie Batulani Mushosi-Tamba⁴

¹Faculty of Natural Health Science, Bircham International University, Department of Toxicology, Madrid, Spain.
²The Provincial General Reference Hospital of Bukavu, Bukavu, Democratic Republic of the Congo.
³Department of Pharmacy, Official University of Bukavu (U.O.B), Bukavu, Democratic Republic of the Congo.
⁴Department of Anesthesiology at Félix Houphouët Boigny University (UFHB), Abidjan, Ivory Coast.

Background: Acute intoxications result from intentionally or accidentally taking a relatively significant amount of a chemical substance which triggers disturbances in the level of psychophysiological functions, the complications of which may lead to mental disorders, physical causalities, and death. Any acute intoxication mostly requires emergency care. Objective: To highlight the prevalence, history, clinical features, emergency treatment, and prediction of acute intoxication cases referred to the emergency services at the Provincial General Reference Hospital in Bukavu, DR-Congo. Methods: A retrospective cross-sectional study was conducted from January 2021 to October 2022 based on an analysis of patients’ medical files. Triage was performed among all-type of patient files recorded in the computerized hospital database Ebale-Sante to sort cases of intoxication. Results: During the observational period, 3966 emergency admissions were counted, of which 321 (8.09%) patients were identified as having acute intoxication. Among these, 100 files that containing sufficient information fit the quality criteria for this study’s analysis. The victims were infants, adolescents and adults aged 1 - 45 years, and 52% were female and 48% were male. Most cases were accidental and, occurred at home, and the victims were driven to the hospital within 2 - 24 hours. The substances consumed included household products, drugs, and herbs. Resuscitation care, antidotes and supportive symptomatic medications ensured that 85% were healed and 10% experienced sequelae; however, 5% died. Conclusion: Acute intoxication occurs in infants mostly accidentally though the ingestion of household products and medicines. Furthermore, suicide cases may occur in traumatized adolescents and discordant couples. People should be informed about how to store hazardous products (e.g.: drugs, household products and pesticides), which should not be available to children, to avoid unintentional poisoning. Special training in clinical toxicology is required to reduce treatment failure.

Acute Intoxication, Patients, Emergency, Provincial General Reference Hospital, Bukavu

Mupendwa, B. , Murhi, E. , Mulinganya, G. , Imani, M. , Mateso, K. , David, S. , Ntokamunda, J. and Mushosi-Tamba, E. (2023) Assessment of Acute Poisoning Cases in Emergency Department of the Provincial General Reference Hospital in Bukavu, DR-Congo. Advances in Infectious Diseases, 13, 233-248. doi: 10.4236/aid.2023.132022.