Author(s)

Amal Hamami, Maria Rkain, Madiha Benhachem, Ayyad Ghannam, Aziza Elouali, Abdeladim Babakhoua, Noufissa Benajiba

Department of Pediatrics, Faculty of Medicine and Pharmacy of Oujda, Mohammed first University, Oujda, Morocco.

Variable Common Immune Deficiency (VCID) is a very heterogeneous condition both clinically and immunologically. It is a group of molecular abnormalities responsible for a defect in antibody production leading to hypogammaglobulinemia often associated with autoimmune and/or lymphoproliferative manifestations. Late Onset Combined Immune Deficiency (LOCID) is a type of Variable Common Immune Deficiency (VCID) defined by a defect in antibody production (IgG and IgA ± IgM type), profound CD4 T-cell lymphopenia and frequent opportunistic infections. LOCID has been considered as a distinct entity from VCID due to its particular clinical and immunological profile.

Haemolytic Anaemia, LOCID, Immune Deficiency, Child

Hamami, A. , Rkain, M. , Benhachem, M. , Ghannam, A. , Elouali, A. , Babakhoua, A. and Benajiba, N. (2023) Late Onset Combined Immune Deficiency (LOCID) Revealed by a Haemolytic Anaemia in a Child: A Case Report. Open Journal of Pediatrics, 13, 347-351. doi: 10.4236/ojped.2023.133040.