Open Journal of Pediatrics

Volume 13, Issue 2 (March 2023)

ISSN Print: 2160-8741   ISSN Online: 2160-8776

Google-based Impact Factor: 0.45  Citations  

Congenital Chylothorax Treated with Oral Sildenafil—Case Report from Nigeria and Review of Literature

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DOI: 10.4236/ojped.2023.132024    66 Downloads   606 Views  Citations

ABSTRACT

Congenital chylothorax, a condition in which chyle accumulates in the pleural cavity, is extremely rare. The reported incidence is 1 in 24,000 births. Medical treatment using octreotide as well as chemical and surgical pleurodesis has been reported, but also few reports on the successful use of Sildenafil exists. We herein report a case of congenital chylothorax referred to our Hospital at 7 days-old. Sildenafil was introduced on day 6 post intubation. Before the introduction of sildenafil, the peak total daily drainage was 106 ml/kg/day (340 mls/day), and after sildenafil was introduced, the total daily drainage dropped progressively to 10 ml/kg/day by day 11 post intubation. This case report highlights the successful use of oral Sildenafil for treatment of congenital chylothorax and also peculiarities of management related to a resource- constrained developing country setting in Africa.

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Uzodimma, C. , Sanni, S. , Madise-Wobo, D. and Uzodimma, C. (2023) Congenital Chylothorax Treated with Oral Sildenafil—Case Report from Nigeria and Review of Literature. Open Journal of Pediatrics, 13, 189-195. doi: 10.4236/ojped.2023.132024.

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