Author(s)

Najlae Nassiri, Hajar Boudarbala, Ayyad Ghanam, Aziza El Ouali, Abdeladim Babakhouya, Maria Rkain

Department of Pediatrics, Mohamed VI University Hospital Center, Oujda, Morocco.

Chickenpox is a common infectious disease in childhood, usually benign. It can be severe in immunocompromised patients and eventually fatal with mul-ti-visceral involvement. The complications affect 4% - 8% of cases and are dominated by bacterial superinfections, related mainly to staphylococcus and streptococcus. We report 3 cases of chickenpox in patients diagnosed with acute lymphoblastic leukemia. All the patients consulted for a febrile eruption made of multiple cutaneous lesions of different ages with umbilical vesicles which could retain the diagnosis of varicella. Our patients received in intrave-nous antiviral treatment for 10 days associated with antibiotic therapy (ceftri-axone and amikacin). The evolution was marked by a clinical-biological im-provement, with only one death related to a delay of consultation. Our study agrees with the data in the literature concerning the frequency of occurrence of complications and death in immunocompromised patients.

Chickenpox, Immunocompromised, Aciclovir, Child

Nassiri, N. , Boudarbala, H. , Ghanam, A. , El Ouali, A. , Babakhouya, A. and Rkain, M. (2023) Chickenpox in Immunocompromised Patients about 3 Case Reports. Open Access Library Journal, 10, 1-5. doi: 10.4236/oalib.1109663.