Author(s)

Seydou Sy^1,2*, Magara Samaké^3,4, Aboubacar Sidiki Fofana³, Atabieme Kodio¹, Oligue Prudence Oman¹, Djibril Sy^2,5, Hamadoun Yattara^1,2, Djénèba Diallo^1,2, Sah Dit Baba Coulibaly¹, Nouhoum Coulibaly¹, Modi Sidibé¹, Alkaya Touré¹, Moustapha Tangara^1,3, Mamadou Lamine Diakité^2,6, Assétou Soukho Kaya^2,5, Saharé Fongoro^1,2

¹Nephrology and Hemodialysis Department, University Teaching Hospital of Point-G, Bamako, Mali.
²Faculty of Medicine and Odontostomatology, University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali.
³Nephrology Unit, Fousseyni Daou Hospital in Kayes, Kayes, Mali.
⁴National Center for Scientific and Technological Research (CNRST), Bamako, Mali.
⁵Department of Internal Medicine, University Teaching Hospital of Point-G, Bamako, Mali.
⁶Department of Urology, University Teaching Hospital of Point-G, Bamako, Mali.

Background: The term urinary lithiasis (UL) from the Greek “lithos” refers to the disease characterised by the result of abnormal precipitation of normal constituents of the urine within the urinary tract. The aim of this work was to determine the frequency of obstructive renal failure (ORF) of lithiasis origin and to describe the therapeutic indications. Methods: This was a retrospective prospective study in patients hospitalised in the nephrology department of Point G University Hospital for ORF of lithiasis origin over a 26-month period from 1 January 2018 to 1 February 2020 inclusive. Results: Among 1898 hospitalized patients, 32 met the inclusion criteria, i.e. a frequency of 1.7%. The male sex was 68.75% with a sex ratio of 2.2. The mean age was 48.38 ± 13.423 years with extremes of 20 and 65 years. Dysuria and urinary bilharzia were the main uro-nephrological antecedents, accounting for 25% of the cases each. Pain syndrome was the main functional sign, accounting for 100%. Ultrasound of the urinary tract (n = 28) showed stones in 92.85%. These stones were bilateral in 22.22% of cases. The dilatation was pyelocalic in 14 cases (51.8%). The uroscanner showed a pyelic location of the stones in both kidneys; 42.1% on the right and 33.3% on the left. Hydronephrosis was the most common dilatation: 37.8% on the right and 29.7% on the left. Renal lithiasis was complicated by acute kidney injury (ARI) in 17 cases (53.1%) versus 15 cases (46.9%) of chronic kidney disease (CKD). Urethral catheter was the means of drainage in 24 (75%) followed by nephrostomy in 8 cases (25%). Nephrolithotomy accounted for 9.4% of cases. The case fatality rate was 28.12% (9 cases). Deaths occurred in the context of uraemic coma 6 cases and cardiorespiratory arrest 3 cases. Conclusions: The management of urinary lithiasis complicated by renal failure calls for the correction of hydrolytic disorders, drainage of the excretory tract and treatment of the stone, of which percutaneous nephrolithotomy seems to be the modality of choice.

Renal Failure, Urinary Lithiasis, Nephrology, University Teaching Hospital of Point-G

Sy, S. , Samaké, M. , Fofana, A. , Kodio, A. , Oman, O. , Sy, D. , Yattara, H. , Diallo, D. , Coulibaly, S. , Coulibaly, N. , Sidibé, M. , Touré, A. , Tangara, M. , Diakité, M. , Kaya, A. and Fongoro, S. (2022) Renal Failure of Lithiasis Origin: Frequency and Management in the Nephrology and Haemodialysis Department of the Point G University Hospital in Mali. Open Journal of Nephrology, 12, 276-292. doi: 10.4236/ojneph.2022.123029.