Left Ventricular Diastolic Dysfunction and Silent Myocardial Ischemia amongst Asymptomatic Type 2 Diabetic Patients in Two Referral Hospitals in Cameroon ()
Author(s)
Joshua Njimbuc Walinjom1*,
Jerome Boombhi1,2,
Martine Etoa3,
Collins Chenwi Ambe1,4,
Emerentia Eho1,
Alain Menanga1,2,
Samuel Kingue1,2#
Affiliation(s)
1Faculty of Medicine and Biomedical Sciences (FMBS), University of Yaoundé I, Yaoundé, Cameroon.
2Medical and Cardiology Unit, General Hospital Yaoundé, Yaoundé, Cameroon.
3Central Hospital Yaoundé, Yaoundé, Cameroon.
4Mvangan District Hospital, Mvangan, Cameroon.
ABSTRACT
Background: Cardiovascular events, the leading cause of death among diabetic patients, are usually under-diagnosed due to subclinical presentation. Methods: We conducted a cross-sectional study from March-2019 to September-2020, in two reference hospitals in Yaoundé, Cameroon, to assess the prevalence of asymptomatic Left Ventricular Diastolic Dysfunction (LVDD) and Silent Myocardial Infarction (SMI) and potentially associated factors. Results: Out of 95 participants (mean age ± SD: 43 ± 7 years; M/F sex-ratio 1.6), 22 (23.1%; 95% CI: 15.8% - 32.6%) had LVDD and fewer (n = 13, 13.6%; 95% CI: 8.2% - 22.0%) had SMI, p = 0.86. Though not statistically significant, patients with ≥5 years diabetes duration, as well as patients with HbA1C ≥ 7.5% had two-fold increased risk of LVDD (p = 0.22 and p = 0.15 respectively). LVDD was significantly higher in patients with SMI (29% vs 6.3%, p < 0.05). Conclusion: The significant presence of asymptomatic cardiovascular manifestations in this population entails mandatory preventive screening, especially, in patients with long standing diabetes and poor glycemic control, to allow timely detection and management.
Share and Cite:
Walinjom, J. , Boombhi, J. , Etoa, M. , Ambe, C. , Eho, E. , Menanga, A. and Kingue, S. (2022) Left Ventricular Diastolic Dysfunction and Silent Myocardial Ischemia amongst Asymptomatic Type 2 Diabetic Patients in Two Referral Hospitals in Cameroon.
World Journal of Cardiovascular Diseases,
12, 374-381. doi:
10.4236/wjcd.2022.127037.
Cited by
No relevant information.