Author(s)

Diagne Bineta Jho^1*, Abid Hakima², Ibtissam El Harch¹, Soumaya Benmaamar¹, Bourkhime Hind¹, Bahra Nassiba¹, Baldé Mamadou Saliou³, Condé Passy¹, Nada Otmani¹, Mohammed El Abkari², Mohamed Amine Berraho¹, Nabil Tachfouti¹, Samira El Fakir¹

¹Laboratory of Epidemiology, Clinical Research and Community Health Faculty of Medicine and Pharmacy, Fez, Morocco.
²Hepatogastroenterology Department, Hassan II University Hospital Center, Fez, Morocco.
³Hemodialysis Nephrology Department, Donka University Hospital Center, Conakry, Guinea.

Introduction: Hepatitis B or C virus infection is one of the most common liver infections leading to altered health-related quality of life (HRQoL) in patients. The goal of this study was to assess the quality of life of patients infected with hepatitis B or C virus and to determine the factors that might be associated with worse outcomes. Methods: A cross-sectional study was conducted in patients aged 18 years and over followed on an outpatient basis at the teaching hospital Hassan II in Fez for hepatitis B or C. These patients were asked to complete the SF-12 questionnaire file which is the short form of the quality measurement scale of life SF-36. Sociodemographic, clinical and economic information was collected. A descriptive analysis was carried out, then a univariate analysis in search of factors associated with quality of life, and finally a multivariate analysis by linear regression was carried out adjusting for possible confounding factors. Results: A total of 94 patients whose mean age was 55.69 ± 13.25 years met the inclusion criteria. The physical quality of life was altered with an average of 41.98 ± 12.67. Hepatitis C virus infection (β = -6.802; 95% CI = (-12.05; -1.55)), cirrhosis (β = -6.947, 95% CI = (-12.04; -1.84)) and lack of employment (β = -8.48, 95% CI = (-13.18; -3.77)) were the factors associated with poor quality of life. The mental quality of life (MCS) was also altered with an average of 46.32 ± 12.84. In multivariate analysis we found that participants with hepatitis C (β = 7.444, 95% CI = (2.14; 12.74)), unemployed (β = 6.697, 95% CI (2.28; 11.11)) and having received treatment (β = 8.295, 95% CI (2.95; 13.63) had a better mental quality of life, while alcoholics had an impaired mental quality of life (β = -8.105, 95% CI (-15.28; -0.92)). Conclusion: Quality of life is altered in patients with chronic hepatitis regardless of type.

Quality of Life, Chronic Hepatitis, Hepatitis B Virus, Hepatitis C Virus, SF12, Health-Related Quality of Life, Morocco

Jho, D.B., Hakima, A., El Harch, I., Benmaamar, S., Hind, B., Nassiba, B., Saliou, B.M., Passy, C., Otmani, N., El Abkari, M., Berraho, M.A., Tachfouti, N. and El Fakir, S. (2022) Quality of Life and Associated Factors in Patients Infected with Hepatitis B and C Virus in a Moroccan Region: A Cross-Sectional Study. Open Access Library Journal, 9, 1-13. doi: 10.4236/oalib.1108781.