Assessments of Antibacterial and Antioxidant Properties in the Methanolic and Aqueous Leaf Extracts of Pistacia lentiscus against Different Antibiotic Resistance Pathogenic Bacteria ()
ABSTRACT
The current study was carried out to determine the
bioactivity of P. lentiscus leaf extracts as potential antibacterial and antioxidant properties. The plant
extracts were examined for antibacterial
activity against antibiotic-resistant Staphylococcus aureus, Staphylococcus haemolyticus, Pseudomonas aeruginosa, and Proteus mirabilis using the agar well method (according to the
guidelines of Clinical and Laboratory
Standard Institute). The antioxidant potential of 3 plant leaf extracts
was determined by their ability to convert Fe3+ to Fe2+ and scavenge the DPPH free radical. At all concentrations studied, the
methanolic leaf extract had higher total phenolic and flavonoid content, as well as stronger antioxidant and
antibacterial inhibitory activity compared to aqueous extract. Our
findings with P. aeruginosa were especially interesting, because this bacterium was inhibited by methanol
extract than that of the reference
antibiotics. The results also demonstrated a link between DPPH radical
scavenging ability, reducing power, and total phenolic and flavonoid content of
plant extracts (r > 0.97, R2 > 0.95, P = 0.01). As a result,
the methanolic leaf extract of the chosen plant might be employed as an
effective antioxidant and antibacterial agent for the treatment of a variety of
morbidities.
Share and Cite:
Alhadad, A. , Salem, G. , Elmhdwi, M. , Hussein, S. and Elshareef, S. (2022) Assessments of Antibacterial and Antioxidant Properties in the Methanolic and Aqueous Leaf Extracts of
Pistacia lentiscus against Different Antibiotic Resistance Pathogenic Bacteria.
Advances in Bioscience and Biotechnology,
13, 113-133. doi:
10.4236/abb.2022.133005.