Helicobacter pylori Infection and Gastroduodenal Lesions: Prevalence and Associated Factors in Cote d’Ivoire ()
ABSTRACT
Objective: The objective is to determine the prevalence of Helicobacter pylori (Hp) infection
and highlight the determinants of the infection as well as the gastric
histopathological lesions associated with this infection. Methods: This
is a retrospective study carried out from August 01, 2015 to December 31, 2020
in Bouaké. It included all patients with gastric and/or duodenal lesion on
upper gastrointestinal endoscopy in whom gastric biopsies and histopathology
results are available. Results: The study involved 510 patients (301 men
and 209 women). The prevalence of Hp was 66.47% (339/510 patients). The
presence of Hp was not significantly related to age and gender.
Epigastralgia was the most common indication with no significant difference
between the positive and negative Hp groups (65.37% vs 34.63%, p =
0.35). A significant difference was only observed for duodenal ulcers (84.31% Hp+
vs 15.69% Hp-, p = 0.004). Regarding histological lesions: Chronic
and active gastritis was strongly related to the presence of Hp (p <
0.05). Intestinal metaplasia and gastric atrophy were not significantly
associated with the presence of Hp. These precursor lesions of gastric
cancer (metaplasia and atrophy) were, however, significantly related to chronic
gastric disease with p = 0.02 and p < 0.001, respectively. Conclusion: The prevalence of Hp is high in Bouaké. Our study confirms the link
between Hp infection and chronic and
active gastritis.
Share and Cite:
Diakité, M. , Koné, A. , Aké, A. , Koffi, K. , Okon, A. and Diallo, K. (2022)
Helicobacter pylori Infection and Gastroduodenal Lesions: Prevalence and Associated Factors in Cote d’Ivoire.
Open Journal of Gastroenterology,
12, 27-35. doi:
10.4236/ojgas.2022.122003.