Author(s)

Hector Giancarlo Torres-Nuño¹, Walter Angel Trujillo-Rangel¹, Jorge Barrera-Alcocer², Miriam Méndez del Villar³, Diana Mercedes Hernández-Corona³, Sylvia Elena Totsuka-Sutto¹, Leonel García Benavides^3*

¹Institute of Therapeutics and Clinical Experimentation, Department of Physiology, Health Sciences University Center (CUCS), University of Guadalajara (UDG), Guadalajara, Mexico.
²Obesity and Diabetes Research Laboratory, Faculty of Chemistry and Biological Sciences, Autonomous University of Guerrero (UAGro), Chilpancingo, Mexico.
³Multidisciplinary Health Research Center, Biomedical Sciences Department, Tonala University Center (CUT), University of Guadalajara (UDG), Guadalajara, Mexico.

Nowadays, fat transfer is an accepted technique that has been popularized in clinical practice, during which large volumes of fat are strategically relocated to increase and improve the contour of the body. In the present study, we investigated the histological and morphometric changes after large volumes of fat were grafted within the subcutaneous cellular tissue. An experimental study was designed using four 3-month-old male pigs. One hundred cc of decanted fat tissue was transferred into the right leg. Volume augmentation achieved by auto lipo-injecting within the subcutaneous cellular tissue persisted up to two months. Although there is a reduction in cell number and size, an increased amount of extracellular matrix and the presence of oily cysts and microcalcifications were observed. Conclusion: The volume augmentation, which is achieved by autologous fat transfer in large quantities in subcutaneous cellular tissue, can remain for months.

Autologous Fat Transfer, Adipose Tissue Transplant, Autologous Fat Injection, Gluteal Augmentation

Torres-Nuño, H. , Trujillo-Rangel, W. , Barrera-Alcocer, J. , del Villar, M. , Hernández-Corona, D. , Totsuka-Sutto, S. and Benavides, L. (2021) Histological Analysis and Morphometric Changes after Autologous Fat Grafting in Large Volumes on Pigs. Journal of Cosmetics, Dermatological Sciences and Applications, 11, 371-380. doi: 10.4236/jcdsa.2021.114030.