Author(s)

Jing Wu^1*#, Shuaishuai Niu^2*, Guan Li^2*, Qing Tian^3*, Ying Xiang^2,3#

¹Department of Morphology, School of Basic Medicine, Health Science Center, Yangtze University, Jingzhou, China.
²Laboratory of Oncology, Center for Molecular Medicine, School of Basic Medicine, Health Science Center, Yangtze University, Jingzhou, China.
³Department of Cell Biology and Genetics, School of Basic Medicine, Health Science Center, Yangtze University, Jingzhou, China.

Tumor is a serious disease that threatens human health and has a high mortality. Chemotherapy is the most commonly used treatment, but it has a lot of side effects due to its toxicity. It has been found that ginsenosides exert an effective antitumor role. Ginsenosides are a class of triterpenoid saponins primarily found in the plant genus Panax. Many monomer components are studied, the most often investigated are Rg3, and Rh2, etc. Reports have shown that ginsenosides can inhibit tumor cells by suppressing proliferation and metastasis, and promoting apoptosis. In addition, ginsenosides can enhance sensitivity to conventional chemotherapeutic drugs. In this review, the recent articles about anti-tumor of ginsenosides were reviewed to promote the further development of anti-tumor therapy.

Ginsenosides, Autophagy, Apoptosis, Proliferation, Metastasis

Wu, J. , Niu, S. , Li, G. , Tian, Q. and Xiang, Y. (2021) Antitumor Effect of Ginsenosides: A Systematic Review. Yangtze Medicine, 5, 207-225. doi: 10.4236/ym.2021.53020.