About a Case of Chronic Myeloid Leukemia and Pregnancy - Open Journal of Obstetrics and Gynecology

OJOG > Vol.11 No.9, September 2021

Open Journal of Obstetrics and Gynecology

Volume 11, Issue 9 (September 2021)

ISSN Print: 2160-8792 ISSN Online: 2160-8806

Google-based Impact Factor: 0.37 Citations h5-index & Ranking

About a Case of Chronic Myeloid Leukemia and Pregnancy ()

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Download as PDF (Size: 282KB) PP. 1190-1195

DOI: 10.4236/ojog.2021.119112 120 Downloads 1,126 Views

Author(s)

M. A. D. Sengeyi¹, S. J. Mokassa^1*, A. J. Lumaya¹, M. R. Mbungu¹, J. J. Malemba²

Affiliation(s)

¹Department of Gynecology and Obstetrics, Department of Obstetrics, University Clinics of Kinshasa, Kinshasa, Democratic Republic of Congo.
²Department of Internal Medicine, Hematology Service, University Clinics of Kinshasa, Kinshasa, Democratic Republic of Congo.

ABSTRACT

Chronic myeloid leukemia (CML) associated with pregnancy is a very rare situation (less than one case per 100,000 pregnancies). It raises a serious ethical and therapeutic problem because chemotherapy during pregnancy can expose the fetus to various complications such as congenital malformations, abortion and intra uterine growth restriction. Inhibitors of tyrosine kinase are the most widely used molecules but without much certainly about their non-teratogenic effects. This is a report case of pregnancy occurring in a patient with Imatinib for CML replaced by Hydrea who gave birth to a healthy newborn with no congenital malformation.

KEYWORDS

Chronic Myeloid Leukemia, Pregnancy, Tyrosine Kinase Inhibitors

Share and Cite:

Sengeyi, M. , Mokassa, S. , Lumaya, A. , Mbungu, M. and Malemba, J. (2021) About a Case of Chronic Myeloid Leukemia and Pregnancy. Open Journal of Obstetrics and Gynecology, 11, 1190-1195. doi: 10.4236/ojog.2021.119112.

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