Author(s)

Hamadoun Yattara¹, Djibril Mamadou Couliblay², Nouhoum Coulibaly^1*, Pamela Samiza¹, Seydou Sy¹, Arboncana Maiga², Djeneba Diallo¹, Moustapha Tanagra¹, Alkaya Touré¹, Magara Samaké³, Niagalé Diakité³, Aboubacar Sidiki Fofana³, Ibrahim Izetiengou Maiga², Sahare Fongoro¹

¹Nephrology and Hemodialysis Department of the Point G University Hospital, Bamako, Mali.
²Medical biology Laboratory Service of the Point G University Hospital, Bamako, Mali.
³Nephrology Department of the Regional Hospital of Kayes, Kayes, Mali.

Introduction: Morbidity and mortality in paediatric practice is dominated in Africa by malaria, diarrhoeal diseases and acute respiratory infections. Aim: In order to evaluate the Glomerular Filtration Rate (GFR) with the formulas commonly used by medical laboratories, we proposed to undertake this study. Patients and Method: This was a descriptive, prospective and cross-sectional study conducted at the PA and KA medical biology laboratory in Bamako Hamdalaye ACI 2000 in collaboration with the medical biology and hospital hygiene laboratory service at the Point G University Hospital. Results: During the study period, we recruited 360 subjects, 189 of whom were male (52.5%) and 171 female (47.5%). The mean age was 8.75 ± 4.8 years with extremes of 1 and 17 years. Subjects aged 15 to 17 years were the most numerous. The reference means GFR of the subjects according to age was with the SCHWARTZ formula 179.16 ± 50.47 with extremes of 173.93 and 184.39; with CKD-Epi 37.63 ± 11.25 with extremes of 36.46 and 38.79; with MAYO 107.87 ± 18.11 with extremes of 105.99 and 109.75 and MDRD 350.83 ± 251.15 with extremes of 324.79 and 376.86. Conclusion: The Mayo formula showed a better distribution around the mean than other formulas for estimating the glomerular filtration rate.

Glomerular Filtration Rate, Reference Value, Young Subjects

Yattara, H. , Couliblay, D. , Coulibaly, N. , Samiza, P. , Sy, S. , Maiga, A. , Diallo, D. , Tanagra, M. , Touré, A. , Samaké, M. , Diakité, N. , Fofana, A. , Maiga, I. and Fongoro, S. (2021) Estimation of Glomerular Filtration Rate: Which Formula to Apply in G-Spot Subjects Aged 1 - 17 Years?. Open Journal of Nephrology, 11, 397-402. doi: 10.4236/ojneph.2021.113032.