Author(s)

Tchente Nguefack Charlotte^1,2*, Bourdanne Tekouake Didier¹, T. Nana Njamen^2,3, Nda Mefo’o Jean Pierre^1,4, Ekono Michel Roger¹, Essome Henri¹, Tsingaing Kamgaing Jacques⁵, Gwet Bell Ernestine⁶, Sandjon Guy⁷, Halle Ekane Edie Gregory^2,3

¹Faculty of Medicine and Pharmaceutical Science, University of Douala, Douala, Cameroon.
²Department of Gynecology and Obstetrics, Douala General Hospital, Douala, Cameroon.
³Faculty of Health Sciences, University of Buea, Buea, Cameroon.
⁴Department of Biology, Douala General Hospital, Douala, Cameroon.
⁵Bel Air Plus Clinic Douala, Douala, Cameroon.
⁶Odyssée Medical Clinic Douala, Douala, Cameroon.
⁷Clinique de l’Aéroport Douala, Douala, Cameroon.

The objective was to assess the outcome of pregnancies after assisted reproductive technology (ART). It was a case-control study carried out in four health facilities in Douala-Cameroon, over a period of five years. The cases were pregnant women who conceived through ART and the controls were those who conceived naturally. Cases and controls were matched for maternal age and parity (one case for two controls). A logistic regression analysis was used to compute Odds ratios. Statistical significance was set at 0.05. A total of 174 women who conceived through ART and 348 who conceived naturally were enrolled. Some independent factors associated with ART were: age over 45 years [aOR: 7.55; 95% CI (1.55 - 36.76); p: 0.01], twin pregnancies [aOR: 16.55; 95% CI (7.91 - 34.60); p < 0.01], Cervical cerclage [aOR: 3.04; 95% CI (1.23 - 7.50); p: 0.01], miscarriages [aOR: 11.73; 95% CI (5.07 - 27.10); p: 0.01], elective cesarean section [aOR: 4.63; 95% CI (2.27 - 9.45); p: 0.01] and low birth weight [aOR: 3.32; 95% CI (1.90 - 5.82); p < 0.01]. Women who conceived by ART were older with higher rates of multiple pregnancy and complications. We recommend transfer of a single embryo.

Pregnancy Outcome, Assisted Reproductive Technology, Douala

Charlotte, T. , Didier, B. , Njamen, T. , Pierre, N. , Roger, E. , Henri, E. , Jacques, T. , Ernestine, G. , Guy, S. and Gregory, H. (2021) Pregnancies Outcome after Assisted Reproductive Technology: A Multicenter Case Control Study in a Low Income Setting Douala, Cameroon. Open Journal of Obstetrics and Gynecology, 11, 720-731. doi: 10.4236/ojog.2021.116067.