Author(s)

Kaba Condé^1,2, Carlos Othon Guelngar², Awada Mohamed¹, Igué Kadidjatou², Douna Granga Daouya³, Mamadou Ciré Barry⁴, Mamadou Hady Diallo², Karinka Diawara², Konaté Mamady², Touré Moriba¹, Fodé Abass Cissé²

¹Department of Rheumatology, Academic Hospital, University of Conakry, Conakry, Guinea.
²Department of Neurology, Academic Hospital, University of Conakry, Conakry, Guinea.
³Department of Pediatric, Mother and child Hospital, Ndjamena, Chad.
⁴Department of Pediatric, Academic Hospital, University of Conakry, Conakry, Guinea.

Secondary hypertrophic osteoarthropathy, or Pierre-Marie Bamberger syndrome, is characterized by the association of digital clubbing, polyarthritis and periostitis affecting the long bones. Most commonly it is a paraneoplastic syndrome associated with lung cancer in 80% of cases. We report the case of a 49-year-old female patient who is actively smoking, one pack per day for 20 years. Seen in consultation for pain and swelling of the hands, elbows, knees, ankles, and feet evolving for about 5 months, associated with a poorly differentiated pulmonary adenocarcinoma. On history, she told us about a weight loss of about 8 kg, no fever, no cough, no family history of inflammatory rheumatism or cancer. Bilateral digital clubbing was noted. The diagnosis was based on imaging and histology. Treatment with nonsteroidal anti-inflammatory drugs (NSAIDs) and chemo-radiotherapy was started.

Hypertrophic Osteoarthropathy, Pulmonary Adenocarcinoma, Guinea

Condé, K. , Guelngar, C. , Mohamed, A. , Kadidjatou, I. , Daouya, D. , Barry, M. , Diallo, M. , Diawara, K. , Mamady, K. , Moriba, T. and Cissé, F. (2021) Secondary Hypertrophic Osteoarthropathy or Pierre-Marie Syndrome Bamberger: Clinical Case and Literature Review. Open Journal of Rheumatology and Autoimmune Diseases, 11, 73-78. doi: 10.4236/ojra.2021.112009.