Rejuvenation of Ovary and Thin Endometrium by Autologous PRP Injection in POR and Recurrent Implantation Failure - Advances in Sexual Medicine

ASM > Vol.11 No.1, January 2021

Advances in Sexual Medicine

Volume 11, Issue 1 (January 2021)

ISSN Print: 2164-5191 ISSN Online: 2164-5205

Google-based Impact Factor: 1 Citations

Rejuvenation of Ovary and Thin Endometrium by Autologous PRP Injection in POR and Recurrent Implantation Failure ()

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DOI: 10.4236/asm.2021.111001 1,038 Downloads 4,229 Views Citations

Author(s)

Yazhini Selvaraj, Kanchana Malaisamy

Affiliation(s)

Obstetrics and Gynecology, Ponni Hospital and Fertility Research Centre, Madurai, India.

ABSTRACT

In India, the problem of infertility is growing and in the last 5 years, it has gone up to 20% - 30%. This ongoing prospective clinical study brings forth a novel, innovative, effective, simple, affordable, easily performed outpatient procedure (OP) and a promising therapeutic method in rejuvenating the Ageing Ovaries and Thin Endometrium, with autologous Platelet Rich Plasma (PRP). This clinical study proves to give a better result in rejuvenating Ovary and treating the Thin Endometrium. This pilot study included five women (28 - 44 years) with Poor Ovarian Response (POR), Premature Ovarian Insufficiency (POI) and Perimenopause and Thirty-nine women (22 - 43 years.) with recurrent implantation failure due to Thin Endometrium were subjected to autologous PRP instillation under Ultrasound Guidance, and Hysteroscopic guided PRP. After PRP, a significant output was obtained, with improved Anti Mullerian Hormone (AMH) and Antral Follicle Count (AFC) and out of five women three women conceived by Intra Cytoplasmic Sperm Injection (ICSI). PRP injected in women with Poor Ovarian Response found successful ovarian rejuvenation within 1 - 3 months and had a 60% of pregnancy rate, PRP into the endometrium had 53.8% successful pregnancies. We have not encountered any complications.

KEYWORDS

Platelet Rich Plasma (PRP), Poor Ovarian Reserve (POR), Premature Ovarian Insufficiency (POI), Anti Mullerian Hormone (AMH), Antral Follicle Counts (AFC), Intra Cytoplasmic Sperm Injection (ICSI), Outpatient Procedure (OP)

Share and Cite:

Selvaraj, Y. and Malaisamy, K. (2021) Rejuvenation of Ovary and Thin Endometrium by Autologous PRP Injection in POR and Recurrent Implantation Failure. Advances in Sexual Medicine, 11, 1-15. doi: 10.4236/asm.2021.111001.

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