Author(s)

Yufei Wang¹, Yingcong Xiao², Zhao Shen², Peilu Wang³, He Chang³, Hongjuan Mao³, Xiufen Yao³, Youmin Guo^3*

¹Department of Imaging, Affiliated Hospital of the First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China.
²School of Medical Technology, Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, China.
³Department of Ultrasound, Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, China.

Objective: To explore the application value of high-frequency ultrasound and contrast-enhanced ultrasound in different syndrome types of knee osteoarthritis, and to provide more imaging evidence for clinical diagnosis and treatment. Method: Sixty patients with KOA were selected according to TCM classification, which were mainly divided into Qi stagnation and blood stasis type and cold-dampness blockage type. All knee joints were routinely examined by high frequency ultrasound, and those with synovial hyperplasia were examined by contrast-enhanced ultrasound. High frequency ultrasound is the examination of synovium, cartilage and collateral ligament of knee joint based on two-dimensional ultrasound. Contrast-enhanced ultrasound (CEUS) refers to the contrast examination of synovium in knee joint patients with synovial hyperplasia. Result: Among them, the suprapatellar sac effusion and synovial thickening of Qi stagnation and blood stasis type were more obvious than those of cold-dampness arthralgia type (P < 0.05), and the degree of wear of the intercondylar cartilage of cold-dampness arthralgia type was more obvious than that of Qi stagnation. The blood stasis type is heavier and the meniscus bulge is higher (P < 0.05). The radiography of synovial hyperplasia showed that the area under the curve of Qi stagnation and blood stasis type was higher than that of cold dampness arthralgia type (P < 0.05), and the peak time was significantly shorter than that of cold dampness arthralgia type. There was no statistical difference in effective peak gradient and onset time of type (P > 0.05). Conclusion: To a certain extent, the high-frequency ultrasound and contrast-enhanced ultrasound performance of knee osteoarthritis can be used as a dialectical reference for different TCM syndrome types.

Knee Osteoarthritis, High-Frequency Ultrasound, Contrast-Enhanced Ultrasound Syndrome

Wang, Y. , Xiao, Y. , Shen, Z. , Wang, P. , Chang, H. , Mao, H. , Yao, X. and Guo, Y. (2020) Application Value of High-Frequency Ultrasound and Contrast-Enhanced Ultrasound in Patients with Knee Osteoarthritis with Different TCM Syndromes. Journal of Biosciences and Medicines, 8, 149-156. doi: 10.4236/jbm.2020.812014.