Author(s)

David Randel Christanto^1*, Johanes C. Mose¹, Tety Yuniarti², Muhammad Begawan Bestari³, Yekti Asih Purwestri⁴, Prima Nanda Fauziah⁵

¹Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia.
²Department of Pediatrics, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia.
³Department of Internal Medicine, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia.
⁴Biochemistry Laboratory, Faculty of Biology, Universitas Gadjah Mada, Yogyakarta, Indonesia.
⁵Department of Medical Medical Laboratory Technology, Faculty of Health, Universitas MH, Thamrin, Jakarta, Indonesia.

Preeclampsia is a multisystem disorder that contributes to morbidity and mortality worldwide. Recent studies show that elevated plasma and erythrocytic malondialdehyde (MDA), a marker of lipid peroxidation, has been documented in women with established preelampsia. This study aimed to observe antioxidant properties of black rice bran on preeclampsia. Level of MDA was measured with TBARS (thiobarbituric acid-reactive substances). Results showed that black rice bran has antioxidant properties by significantly decreasing MDA in preeclampsia-induced HUVEC. This makes black rice bran a promising agent which can be further used in preeclampsia treatment.

Antioxidant, Black Rice Bran, MDA, Preeclampsia, TBARS

Christanto, D. , Mose, J. , Yuniarti, T. , Bestari, M. , Purwestri, Y. and Fauziah, P. (2020) The Role of Black Rice Bran (Oryza sativa L. “Sembada Hitam”) on Levels of Malondialdehyde in Induction Human Umbilical Vein Endothelial Cell Serum Preeclampsia. Open Journal of Obstetrics and Gynecology, 10, 1686-1692. doi: 10.4236/ojog.2020.10120152.