Author(s)

Rodrigue Romuald Elien Gagnan Yan-zaou-tou^1,2*, Guirou Nouhoum¹, Bakayoko Seydou¹, Dicko Mahamat Adam^1,3, Sissoko Modibo¹, Sidibé Mohamed Kolé¹, Mbaïkoua Jean Michel², Mananu Innocent Adubango^1,4, Hann T. Fadimé^1,5, Sylla Aly^1,6, Diabaté Nagnan Cheick Rahim¹, Diarra Modibo¹

¹Institute of Tropical Ophthalmology of Africa-Teaching Hospital (CHU-IOTA), Bamako, Mali.
²National University Hospital Center of Bangui-Teaching Hospital (CNHUB), Bangui, Central African Republic.
³National Reference-Teaching Hospital (CHU-RN), N’Djamena, Republic of Chad.
⁴Evangelical Medical Center of Nyankunde-Bunia, Bunia, Democratic Republic of Congo.
⁵Donka University Hospital Center, Donka, Republic of Guinea.
⁶Medical and Surgical Center of the Army, Conackry, Republic of Guinea.

Introduction: Dry Eye Disease (DED) is a multifactorial affection of the tears and the ocular surface. Its prevalence in the world varies between 7% and 33%. To the best of our knowledge, the prevalence of DED in Subsaharan Francophone African countries is not yet known. The objectives of this systematic review were to determine the prevalence of DED, to identify the main risk factors for DED, and to determine the diagnostic and therapeutic management of DED in Subsaharan Francophone African countries. Methodology: This is a systematic review of articles, dealing with DED, published in English or French language from 2010 to 2020. The following key words (Prevalence OR Incidence OR Proportion OR Rate OR Frequency OR Epidemiology OR Distribution) AND (Risk Factors OR Influences) AND (Symptoms or Questionnaire) AND (Clinical Signs OR Clinical Tests) AND (Dry Eye Disease OR Dry Eye Syndrome) AND (Pharmacological Treatment OR Non-pharmacological Treatment OR Management) AND (Benin OR Burkina Faso OR Burundi OR Cameroon OR Cap-Green OR Central African Republic OR Congo OR Congo (Democratic Republic of) OR Ivory Coast OR Gabon OR Guinea OR Guinea-Bissau OR Equatorial Guinea OR Mali OR Madagascar OR Mauritius (island) OR Niger OR Rwanda OR Sao Tome and Principe OR Senegal OR Seychelles OR Chad OR Togo) in French and English were searched on Pubmed, Chocrane database, Google scholar and ICTRP. Articles in English and French were selected from 2010 to 2020. Results: We selected 05 articles on the epidemiology and management of DED in sub-Saharan francophone Africa. The prevalence of DED in sub-Saharan francophone Africa in the articles ranged from 7.5% to 90.4%. DED affects more women than men. The risk factors found were: age over 50 years, diabetes, meibomian gland dysfunction, prolonged use of computers, and glaucomatous anti-glaucoma drugs. The Test of Breack Up Time (TBUT) was commonly used for the clinical diagnosis of dry eye disease in Sub-Saharan Francophone Africa. The therapeutic strategy for DED was not mentioned in any article. Conclusion: DED, a multifactorial and blinding eye disease, is insufficiently explored by eye health professionals in sub-Saharan Francophone Africa. The implementation of a systematic screening program and strategies for the treatment of dry eye disease in at-risk individuals would be beneficial for sub-Saharan Francophone African countries.

Dry Eye Disease (DED), Epidemiology, Diagnosis, Treatment, Sub-Saharan Francophone Africa

Elien Gagnan Yan-zaou-tou, R. , Nouhoum, G. , Seydou, B. , Adam, D. , Modibo, S. , Kolé, S. , Michel, M. , Adubango, M. , Fadimé, H. , Aly, S. , Rahim, D. and Modibo, D. (2020) Systematic Review on the Epidemiology and Management of the Dry Eye Disease in Sub-Saharan Francophone Africa. Open Journal of Ophthalmology, 10, 323-331. doi: 10.4236/ojoph.2020.104035.