The agricultural production of common bean farmers in the DRC is deficient due to several factors: lack of plant disease control, poor farming practices, declining soil fertility and limited use of soil conservation measures such as the application of cattle manure to restore soil fertility. A complete randomized block experiment design with three replicates was carried out in Rimba and Lekpa sites in Ituri Province in order to observe the seed yield of three varieties of common bean (M’Sole, AFR 708 and Shabi rouge) during two cropping seasons (seasons B 2016 and A 2017) following the effects of using organic manure at dose of 0 and 5 t/ha. Results showed that seed yield of common bean varieties fluctuated significantly according to the season, variety, manure input (P < 0.05). Seeds yield means produced under manure application was (953.94 kg/ha) and the local (900.61 kg/ha). Season A 2017 was more productive (927.28 kg/ha) than season B 2016 (727.4 kg/ha). AFR 708 was the most productive variety in Rimba and Lekpa (1231.66 kg/ha and 926.58 kg/ha) and also in Season A 2017 and Season B 2016 (1081.08 kg/ha and 1077.16 kg/ha). Manure application appeared to be one of the main options that would improve common bean seed yield for food security.