Author(s)

Chundong Qiu¹, Haiyan Chen^2*, Xiaohua Huang^3*, Xiaoling Kong¹, Chong Liang⁴, Chunhong Qiu²

¹Department of Obstetrics, The First People’s Hospital of Yulin City, Yulin, China.
²Department of Obstetrics, The Second People’s Hospital of Yulin City, Yulin, China.
³Department of Clinical Laboratory, Yunyang Hospital of Traditional Chinese Medicine, Chongqing, China.
⁴Department of Clinical Laboratory, Red Cross Hospital of Yulin City, Yulin, China.

Objective: To investigate the correlation between deep static color Doppler ultrasound of both lower extremities combined with fibrinolytic system detection in pregnancy-induced hypertension. Methods: A total of 70 normal pregnant women, 70 pregnant women with hypertension during pregnancy, and 50 healthy non-pregnant women in the same period were selected as the research objects. The deep veins of both lower limbs were examined by Rili Erlangshen’s color Doppler ultrasound diagnostic instrument (CDU), and the fibrinolysis system was tested by enzyme-linked immunosorbent assay (ELISA) method and automatic hemagglutination analyzer. Results: Compared with the non-pregnant group, the inner diameters of the left/right femoral vein (CFV) and popliteal vein (POV) in the normal pregnancy group and the pregnancy-induced hypertension group were significantly widened, and the peak blood flow spectrum was significantly reduced. The difference was statistically significant (P < 0.01); FIB, PLG, t-PA, PAI, D-Dimer were significantly increased, the difference was statistically significant (P < 0.01); Compared with the normal pregnancy group, the inner diameter of the left/right femoral vein (CFV) in the hypertensive pregnancy group was significantly wider than that in the normal pregnancy group, and the peak value of the left/right POV blood flow spectrum was significantly lower than that in the normal pregnancy group, the difference was statistically significant (P < 0.01), while the left/right popliteal vein (POV) inner diameter, left/right CFV blood flow peak value did not change significantly from the normal pregnancy group, and the difference was not statistically significant (P > 0.05); FIB, PLG, PAI, D-Dimer of the hypertensive disease group during pregnancy significantly increased, the difference was statistically significant (P < 0.01), while t-PA was not statistically significant (P > 0.05). Conclusion: Normal pregnant women have a hypercoagulable state compared with healthy non-pregnant women, and pregnant women with hypertension during pregnancy are more likely to be in a pre-thrombotic state than pregnant women with normal pregnancy. Deep vein CDU examination of both lower extremities combined with blood fibrinolysis monitoring is of great value in the prevention and treatment of hypertension during pregnancy.

Hypertension during Pregnancy, Prothrombotic State, Color Doppler Ultrasound, Fibrinolysis Index

Qiu, C. , Chen, H. , Huang, X. , Kong, X. , Liang, C. and Qiu, C. (2020) Correlation Study of Color Doppler Examination of Deep Veins of Both Lower Extremities Combined with Fibrinolysis System in Hypertension during Pregnancy. Open Journal of Obstetrics and Gynecology, 10, 981-989. doi: 10.4236/ojog.2020.1080093.