Author(s)

Deniz Avci^*, Ali Çetinkaya

Department of Internal Medicine, Kayseri Training and Research Hospital, Kayseri, Turkey.

Aim: We compared the waist circumferences (WC) of 1214 diabetics with various parameters in real-life conditions. Patients and Method: The study was carried out by reviewing the anthropometric measurements and biochemical analyzes of diabetics and they were analyzed due to WC status of the patients. Results: Mean total cholesterol level was 204.6 ± 47.1 mg/dL in patients with normal WC and 211.6 ± 45.6 mg/dL in patients with increased WC (p = 0.015). Total cholesterol was found to be a risk factor for WC enlargement (OR: 1.003, 95% CI: 1.001 - 1.006, p = 0.015). HDL-cholesterol appeared to be a risk factor for the increase in WC (OR: 1.005, CI: 1.001 - 1.010, p = 0.029). Median triglyceride level was 158 (41 - 975) mg/dL in the normal WC group, while it was 176 (22 - 1379) mg/dL in the patients with increased WC (p < 0.001). Triglyceride was observed as a risk factor for WC increase (OR: 1.002, 95% CI: 1.001 - 1.003, p = 0.004). The serum uric acid level was 4.75 ± 1.6 mg/dL in the normal WC group, while it was 5.09 ± 1.5 mg/dL in the increased WC group (p = 0.002). Serum uric acid level was appeared as a risk factor for increased WC (OR: 1.162, 95% CI: 1.057 - 1.276, p = 0.002). The median serum GGT level was 27 (7 - 174) mg/dL in WC normal group and 28 (8 - 730) mg/dL in increased WC diabetics (p = 0.029). Serum GGT level was a risk factor for increased WC (OR: 1.162, 95% CI: 1.001 - 1.010, p = 0.029). Conclusion: We have demonstrated that the measurement of WC has an important role in diabetes management and is related with inflammatory parameters such as uric acid and GGT.

Diabetes Mellitus, Waist Circumference, Uric Acid, GGT, Inflammation

Avci, D. and Çetinkaya, A. (2019) Uric Acid and GGT Have Causal Relations with Abdominal Obesity: A Real-Life Research in Turkish Population with 1214 Diabetics. Journal of Biosciences and Medicines, 7, 1-14. doi: 10.4236/jbm.2019.72001.