Amyotrophic Lateral Sclerosis (ALS) about 2 Observations in the Neurology Department of the University Hospital of Cocody

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DOI: 10.4236/oalib.1101924    1,121 Downloads   1,845 Views  

ABSTRACT

Amyotrophic lateral sclerosis (ALS) is a rare but serious neurodegenerative disease characterized by progressive muscular paralysis without overall achievement of higher functions, resulting from motor neuron destruction. The present study reports two cases of elderly female patients aged 45 and 54 years, respectively, allowed for a progressive motor deficit of 4 members. Neurological examination found a spastic pyramidal syndrome and a neurogenic syndrome device of 4 members without sensory syndrome. The ENMG revealed a pure motor neurogenic compatible with involvement of the anterior horn of the spinal cord, holding the ALS diagnosis. The standard radiography and cervical MRI were normal. These patients received analgesics, nursing, physiotherapy and psychotherapy. Then they were lost. ALS is a rare disease (incidence: 1.25%). Our patients, with a mean age of 54.5 years, showed clinical and laboratory signs associated with them classically encountered. The diagnosis is suspected in a spastic pyramidal syndrome and neurogenic peripheral syndrome of 4 members but not eliminate cervical spondylotic myelopathy one. The ENMG confirms it. Although the treatment is disappointing, it’s based on the riluzole and palliative care, but the evolution is inexorably toward death.

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Yapo-Ehounoud, C. , Aka-Anghui-Diarra, E. , Amon-Tanoh, M. , Assi, B. , Kouamé-Assouan, A. , Tanoh, C. and Kotchi, E. (2015) Amyotrophic Lateral Sclerosis (ALS) about 2 Observations in the Neurology Department of the University Hospital of Cocody. Open Access Library Journal, 2, 1-6. doi: 10.4236/oalib.1101924.

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