This paper presents the standardization of the Rosenberg Self-Esteem Scale (RSES) in the Greek population. Self-esteem is defined as the positive or negative reflection that the individual has for himself/herself and the belief of being able to cope with the basic challenges of life. The RSES was completed by university students with a mean age of 19. Along with the RSES we administered the Health Locus of Control Scale, the Perceived Stress Scale (PSS), the Stress and Personality Self Test and the self-esteem questionnaire (Darviri & Varvogli). The results on the reliability and validity of the RSES were satisfactory as the internal reliability index crombach a was .80 and the RSES had positive statistical significant relationship with the second questionnaire of self-esteem. We also found statistically significant relationships with stress levels, health locus of control and personality types. It seems that when people attribute their good health to others, they have increased self-esteem in relation to people who attributed their good health to themselves. Furthermore our study showed that women have higher levels of self-esteem than men, an opposite outcome to the one of previous validations. The RSES Greek version is a tool that can be used for the measurement of Self-Esteem in the Greek Population.