Prof. Dan Xie

Sun Yat-Sen University Cancer Center, China

Email: xiedan@sysucc.org.cn

Qualifications

2004 Ph.D., The University of Hongkong, China, Clinical Oncology

1996 M.Sc., Sun Yat-Sen University, China, Pathology

1991 B.Sc., Central South University, China, Medicine

Publications (selected)

1. Zhu W., Cai M.Y., Tong ZT, Dong S.S., Mai S.J., Liao Y.J., Bian X.W., Lin M.C., Kung H.F., Zeng Y.X., Guan X.Y., Xie D. (2012), Overexpression of EIF5A2 promotes colorectal carcinoma cell aggressiveness by upregulatingMTA1 through c-myc to induce epithelial-mesenchymal transition. Gut, 61, 4, 562-575.
2. Zheng F., Liao Y.J., Cai M.Y., Liu Y.H., Liu T.H., Chen S.P., Bian X.W., Guan X.Y., Lin M.C., Zeng Y.X., Kung H.F., Xie D. (2012), The putative tumor suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2. Gut, 61, 2, 278-289.
3. Tong Z.T., Cai M.Y., Wang X.G., Kong L.L., Mai S.J., Liu .YH., Zhang H.B., Liao Y.J., Zheng F., Zhu W., Liu T.H., Bian X.W., Guan X.Y., Lin M.C., Zeng M.S., Zeng Y.X., Kung H.F., Xie D. (2012), EZH2 supports nasopharyngeal carcinoma cell aggressiveness by forming a co-repressor complex with HDAC1/HDAC2 and Snail to inhibit E-cadherin. Oncogene, 31, 5, 583-594.
4. Cai M.Y., Tong Z.T., Zheng F., Liao Y.J., Wang Y., Rao H.L., Chen Y.C., Wu Q.L., Liu Y.H., Guan X.Y., Lin M.C., Zeng Y.X., Kung H.F., Xie D. (2011), EZH2 protein: a promising immunomarker for the detection of hepatocellular carcinomas in liver needle biopsies. Gut, 60, 7, 967-976.
5. He .LR., Zhao H.Y., Li B.K., Zhang L.J., Liu M.Z., Kung H.F., Guan X.Y., Bian X.W., Zeng Y.X., Xie D. (2010), Overexpression of AIB1 negatively affects survival of surgically resected non-small-cell lung cancer patients. Ann Oncology, 21, 8, 1675-1681.