Prof. Nicolas G. Bazan
Louisiana State University Health Sciences Center, USA
Email: nbazan@lsuhsc.edu
Qualifications
1970 Ph.D., Medical School, U. Tucuman
1965 M.Sc., Medical School, U. Tucuman
1958 B.Sc., Colegio Belgrano
Publications(Selected)
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Stark, D.T., Bazan, N.G. Synaptic and extrasynaptic NMDA receptors differentially modulate neuronal COX-2 function, lipid peroxidation, and neuroprotection. J Neurosci. 2011 Sep 28;31(39):13710-21
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Zhou, Y., Sheets, K.G., Knott, E.J., Regan, C.E. Jr., Tuo, J., Chan, C.C., Gordon, W.C., Bazan, N.G. Cellular and 3D Optical Coherence Tomography Assessment During the Initiation and Progression of Retinal Degeneration in the Ccl2/Cx3cr1-deficient Mouse. Exp. Eye Res. 2011 Nov;93(5):636-48
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Cortina, M.S., He, J., Li, N., Bazan, N.G., Bazan, H.E. Recovery of corneal sensitivity, CGRP positive nerves and increased wound healing are induced by PEDF plus DHA after experimental surgery. Arch. Ophthal. 2011 (in press)
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Molina, M.F., Bazan, N.G. The bioactive mediator neuroprotectin D1 derived from docosahexaenoic acid is a homeostatic cell survival sentinel in the nervous system. ASBMB Today 2011 Sep;52(9):1601-8
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Musto, A.E., Gjorstrup, P., Bazan, N.G. The omega-3 fatty acid-derived neuroprotectin D1 limits hippocampal hyperexcitability and seizure susceptibility in kindling epileptogenesis. Epilepsia. 2011 (in press)
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Mattson, M.P., Bazan, N.G. Apoptosis and Necrosis. In Basic Neurochemistry: Molecular, Cellular and Medical Aspects, 8th edition, G.Siegel, R.W. Albers, S.T. Brady, D.L. Price (eds.), 2011 (in press)
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Belayev, L., Lu, Y. M., Bazan, N.G. Brain Ischemia and Reperfusion: Cellular and Molecular Mechanisms in Stroke Injury. In Basic Neurochemistry: Molecular, Cellular and Medical Aspects, 8th edition, G.Siegel, R.W. Albers, S.T. Brady, D.L. Price (eds.), 2011 (in press)
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Bazan, N.G., Halabi, A., Ertel, M., Petasis, N.A. Neuroinflammation. In Basic Neurochemistry: Molecular, Cellular and Medical Aspects, 8th edition, G.Siegel, R.W. Albers, S.T. Brady, D.L. Price (eds.), 2011 (in press)
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Bazan, N.G., Stark, D.T., Petasis, N.A. Lipid Mediators: Eicosanoids, Docosanoids and Platelet-Activating Factor. In Basic Neurochemistry: Molecular, Cellular and Medical Aspects, 8th edition, G.Siegel, R.W. Albers, S.T. Brady, D.L. Price (eds.), 2011 (in press)
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Bazan, N.G., Molina, M.F., Gordon, W.C. Docosahexaenoic Acid Signalolipidomics in Nutrition: Significance in Aging, Neuroinflammation, Macular Degeneration, Alzheimer's and other Neurodegenerative Diseases. Annual Review of Nutrition 2011 31:321-51.
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Stark, D.T., Bazan, N.G. Protectin D1 induces neuronal survival and downregulation of amyloidogenic processing in Alzheimer's disease cellular models. Mol Neurobio, (2011) 2:131-8
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Musto, A.E., Gjorstrup, P., Bazan, N.G. The omega-3 fatty acid-derived neuroprotectin D1 limits hippocampal hyperexcitability and seizure susceptibility in kindling epileptogenesis. Epilepsia (2011) in press
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Musto, A.E., Quebedeaux, T.M., Bazan, N.G. Hippocampal interneuronal cell loss is attenuated by neuroprotectin D1 with concomitant re-establishment of theta/gamma oscillations in status epilepticus. Epilepsia (2011) in press
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Halapin NA, Bazan NG. NPD1 Induction of Retinal Pigment Epithelial Cell Survival Involves PI3K/Akt Phosphorylation Signaling. Neurochem. Res. (2010) 35:1944-1947
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Zhao Y, Calon F, Julien C, Winkler JW, Petasis NA, Lukiw WJ, Bazan NG: Docosahexaenoic acid-derived neuroprotectin D1 induces neuronal survival via secretase- and PPARγ-mediated mechanisms in Alzheimer’s disease models. PLoS ONE (2010) 6:e15816
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Kenchegowda, S., Bazan, N.G., Bazan, H.E. EGF stimulates lipoxin A4 synthesis and modulates repair in corneal epithelial cells through ERK and p38 activation. Invest. Ophthal. Vis. Sci. (2010) in press
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Belayev, L., Khoutorova, L., Atkins, K.D., Eady, T.N., Hong, S., Lu, Y., Obenaus, A., Bazan, NG: Docosahexaenoic acid therapy of experimental ischemic stroke. Transl. Stroke Res. (2010) 2:33-41
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Knott, E.J., Sheets, K.G., Zhou, Y., Gordon, W.C., Bazan, NG: Spatial correlation of mouse photoreceptor-RPE thickness between SD-OCT and histology. Exp. Eye Res. (2011) 92:155-160
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Cui, J.G., Bazan, NG: Agrin down- or up-regulation mediates neuropathic pain. J. Neurosci. (2010) 30:15286-15297