Biography

Prof. Suresh C. Tyagi

University of Louisville, USA


Email: suresh.tyagi@louisville.edu


Qualifications


1980 Ph.D., University of Aligarh, India

1977 M.Phil., University of Aligarh, India


Publications (selected)

  1. Sood HS, Hunt MJ, Tyagi SC. Peroxisome proliferator ameliorates endothelial dysfunction in a murine model of hyperhomocysteinemia, Am J Physiol, 2003; 284: L333-L341.
  2. Camp T, Smiley L, Hayden MR, Tyagi SC. Mechanism of Matrix accumulation and glomerulosclerosis in spontaneously hypertensive rats, J Hyperten, 2003; 21(9): 1719-1727. An editorial on this paper, page: 1627-1630.
  3. Camp TM, Tyagi SC, Senior RM, Hayden MR, Tyagi SC. Gelatinase B (MMP-9) an apoptotic factor in diabetic transgenic mice, Diabetologia. 2003, 46(10): 1438-1445.
  4. Reddy KH, Tjahja IE, Campbell SE, Janicki JS, Hayden MR, Tyagi SC. Expression of MMP activity in idiopathic dilated cardiomyopathy: A marker of cardiac dilatation. Mol Cell Biochem, 2004; 264: 183-191.
  5. Smiley LM, Camp TM, Lucchesi PA, Tyagi SC. Peroxisome proliferator ameliorates endocardial endothelial and muscarinic dysfunction in spontaneously hypertensive rats, Antioxidants & Redox Signaling, 2004, 6(2): 367-374.
  6. Camp TM, Tyagi SC, Aru GM, Hayden MR, Mehta JL, Tyagi SC. Doxycycline ameliorates ischemic and border zone remodeling and endothelial dysfunction after MI in rats, J Heart Lung Transplant, 2004, 23: 729-736.
  7. Cox MJ, Hawkins UA, Hoit BD, Tyagi SC. Attenuation of oxidative stress and remodeling by cardiac inhibitor of metalloproteinase protein transfer, Circulation, 109(17): 2123-2128, 2004.
  8. Shastry S, Tyagi SC. Homocysteine induces metalloproteinase and shedding of ß-1 integrin in microvessel endothelial cells, J Cell Biochem, 2004, 93: 207-213.
  9. Shastry S, Tyagi N, Tyagi SC. Proteomic analysis of Hcy-inhibition of microvascular endothelial cell angiogenesis, Cell Mol Biol; 2004 Dec; 50(8): 931-7.
  10. Carroll JF, Tyagi SC. ECM remodeling in heart of Hcy-mic obese rabbit, Am J Hypertens, 18(5): 692-698, 2005.
  11. Moshal KS, Tyagi N, Henderson B, Ovechkin AV, Tyagi SC. Protease activated receptor and endothelial-myocyte uncoupling in chronic heart failure, Am J Physiol (Heart & Circulatory), 2005 Jun; 288(6): H2770-7.
  12. Tyagi N, Moshal KS, Lominadze D, Ovechkin AV, Tyagi SC. Hcy-dependent cardiac remodeling & endothelial-myocyte coupling in 2K1C Goldblatt hypertension mouse model. Canad J Physiol & Pharmac, 83(7): 583-594, 2005.
  13. Moshal KS, Tyagi N, Moss V, Henderson B, Steed M, Ovechkin A, Aru GM, Tyagi SC. Early induction of matrix metalloproteinase-9 transduces signaling in human heart end stage failure, J Cell Mol Med, 8(3): 704-713, 2005.
  14. Shastry S, Moning L, Tyagi N, Steed M, Tyagi SC. GABA receptors and nitric oxide ameliorate constrictive collagen remodeling in hyperhomocysteinemia, J Cell Physiol, 205(3): 422-7, 2005.
  15. Tyagi N, Moshal KS, Ovechkin AV, Rodriguez W, Steed M, Henderson B, Roberts AM, Joshua IG, Tyagi SC. Mitochondrial mechanism of oxidative stress and systemic hypertension in HHcy, J Cell Biochem, 96: 665-671, 2005.
  16. Passmore JC, Joshua IG, Rowell P, Tyagi SC, Falcone JC. Reduced Alpha Adrenergic Mediated Contraction of Renal Preglomerular Blood Vessels as a Function of Gender and Aging, J Cell Biochem, 96(4): 672-681, 2005.
  17. Tyagi N, Sordis KC, Moshal KS, Ovechkin AV, Tyagi SC. Mechanisms of Homocysteine-Induced Oxidative stress, Am J Physiol Heart & Circulatory Physiol, 289(6): H2649-56, 2005.
  18. Ovechkin AV, Tyagi N, Rodriguez WE, Hayden MR, Moshal KS, Tyagi SC. Role of MMP-9 in endothelial apoptosis in chronic heart failure in mice. J Appl Physiol, 99(6): 2398-405, 2005.
  19. Moshal KS, Sen U, Tyagi N, Henderson B, Steed M, Ovechkin AV, Tyagi SC. Regulation of Hcy-induced MMP-9 by extracellular regulated protein kinase-1/2 (ERK-1/2) pathway, Am J Physiol Cell Physiol, 290(3): C883-91, 2006.
  20. Lominadze D, Roberts AM, Tyagi N, Moshal KS, Tyagi SC. Homocysteine causes cerebrovascular leakage in mice. Am J Physiol Heart & Circulatory Physiol, H1206-13, 2006.

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