Dr. Kenneth Maiese
UMDNJ-New Jersey Med School, USA

Email: wntin75@yahoo.com

Qualifications

1994 Director, Wayne State Univ. Sch. of Medicine, USA

2010 Professor, UMDNJ-New Jersey Med School, USA
2010 Advisory Board of Directors, Cancer Institute of New Jersey, USA

Publications (Selected)

1. Chong, Z. Z, Kang, J-Q, and Maiese, K. Essential cellular regulatory elements for early and late phases of apoptotic oxidative stress in the nervous system. Antiox Redox Signal 6(2), 277-287, 2004.
2. Chong, Z. Z., Kang, J-Q, and Maiese, K. Akt1 drives endothelial cell membrane asymmetry and microglial activation through Bcl-xL and caspase 1, 3, and 9. Exp Cell Res 296(2), 196-207, 2004.
3. Chong, Z. Z., Lin, S.-H., and Maiese, K. The NAD+ precursor nicotinamide governs neuronal surv. during oxidative stress through protein kinase B, FOXO3a and mito. mem. potential. J Cereb Blood Flow Metab 24. 728-743, 2004.
4. Maiese, K. and Chong, Z. Z. Insights into oxidative stress and potential novel therapeutic targets for Alzheimer disease. Restorative Neurol Neurosci 22, 87-104, 2004.
5. Maiese, K, Li, F., and Chong, Z. Z. Erythropoietin in the brain: Can the promise to protect be fulfilled? Trends Pharmacol Sci 25, 577-583, 2004.
6. Maiese, K, Li, F., and Chong, Z. Z. New avenues of exploration for erythropoietin. JAMA 293(1), 90-95, 2005.
7. Chong, Z. Z., Li, F., and Maiese, K. Stress in the brain: Novel cellular mechanisms of injury linked to Alzheimer's disease. Brain Res Brain Res Rev 49(1), 1-21, 2005 (Cited as the TOP25 Hottest Article with the highest download rate).
8. Chong, Z. Z., Li, F, and Maiese, K. Erythropoietin requires NF-κB and its nuclear translocation to prevent early and late apoptotic neuronal injury during β-amyloid toxicity. Curr Neurovasc Res 2(5), 387-399, 2005.
9. Chong, Z. Z., Li, F., and Maiese, K. Activating Akt and the brain's resources to drive cellular survival and prevent inflammatory injury. Histol and Histopath 20, 299-315, 2005.
10. Chong, Z. Z., Li, F., and Maiese, K. Employing new cellular therapeutic targets for Alzheimer's disease: A change for the better? Curr Neurovasc Res 2(1), 55-72, 2005.
11. Maiese, K, Li, F., and Chong, Z. Z. Erythropoietin and cancer. JAMA 293(15), 1858-1859, 2005.
12. Chong, Z. Z., Li, F, and Maiese, K. Oxidative stress in the brain: novel cellular targets that govern cell survival during neurodegenerative disease. Prog Neurobiol 75(3), 207-246, 2005 (Cited as a TOP25 Hottest Article download rate).
13. Chong, Z. Z., Kang, J-Q., Li, F., and Maiese, K. mGluRI targets microglial activation and selectively prevents neuronal cell engulfment through Akt and caspase dependent pathways. Curr Neurovasc Res 2(3), 197-211, 2005.
14. Li, F., Chong, Z. Z., and Maiese, K. Cell life versus cell longevity: The mysteries surrounding the NAD+ precursor nicotinamide. Curr Med Chem 13(8), 883-895, 2006 (Cover article).
15. Chong, Z. Z., Li, F, and Maiese, K. Attempted cell cycle induction in post-mitotic neurons occurs in early and late apoptotic programs through Rb, E2F1, and caspase 3. Curr Neurovasc Res 3(1), 25-29, 2006.
16. Chong, Z. Z., Li, F., and Maiese, K. Group I metabotropic receptor neuroprotection requires Akt and its substrates that govern FOXO3a, Bim, and β-catenin during oxidative stress. Curr Neurovasc Res 3(2), 107-117, 2006.
17. Li, F, Chong, Z. Z., and Maiese, K. Microglial integrity is maintained by erythropoietin through integration of Akt and its substrates of glycogen synthase kinase-3β and nuclear factor-κB. Curr Neurovasc Res 3(3), 187-201, 2006.
18. Chong, Z. Z., Li, F, and Maiese, K. The pro-survival pathways of mTOR and protein kinase B target glycogen synthase kinase-3β and nuclear factor-κB to foster endogenous microglial cell protection. Int J Mol Med 19(2), 263-272, 2007.
19. Chong, Z. Z. and Maiese, K. Erythropoietin employs the phosphatidylinositol 3-kinase pathway, 14-3-3, and FOXO3a nuclear trafficking to foster endothelial cell integrity. Br J Pharmacol 150(7), 839-850, 2007 (Cited by Nature Publishing Group as one of the top articles with the highest download rate).
20. Maiese, K., Morhan, S. D., and Chong, Z. Z. Oxidative stress biology and cell injury during type 1 and type 2 diabetes mellitus. Curr Neurovasc Res 4(1):63-71, 2007.
21. Maiese, K., Chong, Z. Z., and Shang, Y. C. Mechanistic insights into diabetes mellitus and oxidative stress. Curr Med Chem 14(16), 1729-1738, 2007.