Pineapple Juice as a Natural Catalyst: An Excellent Catalyst for Biginelli Reaction

Suresh Patil, Swati D. Jadhav, Sanjeevani Y. Mane

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DOI: 10.4236/ijoc.2011.13019                

Abstract

An efficient and greener synthesis of a series of dihydropyrimidinone (DHPMs) derivatives were accomplished via three-component one-pot cyclocondensation between substituted aryl aldehydes, diketone/ke- toester and urea. This solvent free approach is totally nonpolluting having several advantages such as shorter reaction time, mild reaction conditions, simple workup and reduced environmental impact.

Keywords

Biginelli, Natural Catalyst, Pineapple Juice, Dihydropyrimidinone

Conflicts of Interest

The authors declare no conflicts of interest.

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