[1]
|
Papa, S., Francavilla, A., Paradies, G. and Meduri, B. (1971) The Transport of Pyruvate in Rat Liver Mitochondria. FEBS Letters, 12, 285-288. http://dx.doi.org/10.1016/0014-5793(71)80200-4
|
[2]
|
Halestrap, A.P. and Denton, R.M. (1974) Specific Inhibition of Pyruvate Transport in Rat Liver Mitochondria and Human Erythrocytes by alpha-Cyano-4-hydroxycinnamate. Biochemical Journal, 138, 313-316.
|
[3]
|
Halestrap, A.P. and Denton, R.M. (1975) The Specificity and Metabolic Implications of the Inhibition of Pyruvate Transport in Isolated Mitochondria and Intact Tissue Preparations by alpha-Cyano-4-hydroxycinnamate and Related Compounds. Biochemical Journal, 148, 97-106.
|
[4]
|
Thomas, A.P. and Halestrap, A.P. (1981) Identification of the Protein Responsible for Pyruvate Transport into Rat Liver and Heart Mitochondria by Specific Labelling with [3H]N-Phenylmaleimide. Biochemical Journal, 196, 471-479.
|
[5]
|
Schell, J.C. and Rutter, J. (2013) The Long and Winding Road to the Mitochondrial Pyruvate Carrier. Cancer & Metabolism, 1, 6.
|
[6]
|
Gray, L.R., Tompkins, S.C. and Taylor, E.B. (2014) Regulation of Pyruvate Metabolism and Human Disease. Cellular and Molecular Life Sciences, 71, 2577-2604. http://dx.doi.org/10.1007/s00018-013-1539-2
|
[7]
|
Jeoung, N.H., Harris, C.R. and Harris, R.A. (2014) Regulation of Pyruvate Metabolism in Metabolic-Related Diseases. Reviews in Endocrine & Metabolic Disorders, 15, 99-110. http://dx.doi.org/10.1007/s11154-013-9284-2
|
[8]
|
Palsson-McDermott, E.M. and O’Neill, L.A.J. (2013) The Warburg Effect Then and Now: From Cancer to Inflammatory Diseases. Bioessays, 35, 965-973. http://dx.doi.org/10.1002/bies.201300084
|
[9]
|
Warburg, O., Wind, F. and Negelein, E. (1927) The Metabolism of Tumors in the Body. The Journal of General Physiology, 8, 519-530. http://dx.doi.org/10.1085/jgp.8.6.519
|
[10]
|
Iqbal, M.A., Gupta, V., Gopinath, P., Mazurek, S. and Bamezai, R.N.K. (2014) Pyruvate Kinase M2 and Cancer: An Updated Assessment. FEBS Letters, 588, 2685-2692. http://dx.doi.org/10.1016/j.febslet.2014.04.011
|
[11]
|
Pande, S.V. and Parvin, R. (1978) Pyruvate and Acetoacetate Transport in Mitochondria. A Reappraisal. Journal of Biological Chemistry, 253, 1565-1573.
|
[12]
|
Shearman, M.S. and Halestrap, A.P. (1984) The Concentration of the Mitochondrial Pyruvate Carrier in Rat Liver and Heart Mitochondria Determined with Alpha-Cyano-Beta-(1-phenylindol-3-yl)acrylate. Biochemical Journal, 223, 673- 676.
|
[13]
|
Bricker, D.K., Taylor, E.B., Schell, J.C., Orsak, T., Boutron, A., Chen, Y.C., Cox, J.E., Cardon, C.M., Van Vranken, J.G., Dephoure, N., Redin, C., Boudina, S., Gygi, S.P., Brivet, M., Thummel, C.S. and Rutter, J. (2012) A Mitochondrial Pyruvate Carrier Required for Pyruvate Uptake in Yeast, Drosophila, and Humans. Science, 337, 96-100.
http://dx.doi.org/10.1126/science.1218099
|
[14]
|
Herzig, S., Raemy, E., Montessuit, S., Veuthey, J.L., Zamboni, N., Westermann, B., Kunji, E.R.S. and Martinou, J.C. (2012) Identification and Functional Expression of the Mitochondrial Pyruvate Carrier. Science, 337, 93-96.
http://dx.doi.org/10.1126/science.1218530
|
[15]
|
Brailsford, M.A., Thompson, A.G., Kaderbhai, N. and Beechey, R.B. (1986) The Extraction and Reconstitution of the Alpha-Cyanocinnamate-Sensitive Pyruvate Transporter from Castor Bean Mitochondria. Biochemical and Biophysical Research Communications, 140, 1036-1042. http://dx.doi.org/10.1016/0006-291X(86)90739-4
|
[16]
|
Nalecz, M.J., Nalecz, K.A., Broger, C., Bolli, R., Wojtczak, L. and Azzi, A. (1986) Extraction, Partial Purification and Functional Reconstitution of Two Mitochondrial Carriers Transporting Keto Acids: 2-Oxoglutarate and Pyruvate. FEBS Letters, 196, 331-336. http://dx.doi.org/10.1016/0014-5793(86)80273-3
|
[17]
|
Capuano, F., Di Paola, M., Azzi, A. and Papa, S. (1990) The Monocarboxylate Carrier from Rat Liver Mitochondria. Purification and Kinetic Characterization in a Reconstituted System. FEBS Letters, 261, 39-42.
http://dx.doi.org/10.1016/0014-5793(90)80631-R
|
[18]
|
Nalecz, M.J., Nalecz, K.A. and Azzi, A. (1991) Purification and Functional Characterisation of the Pyruvate (Monocarboxylate) Carrier from Baker’s Yeast Mitochondria (Saccharomyces cerevisiae). Biochimica et Biophysica Acta, 1079, 87-95. http://dx.doi.org/10.1016/0167-4838(91)90028-X
|
[19]
|
Hildyard, J.C.W. and Halestrap, A.P. (2003) Identification of the Mitochondrial Pyruvate Carrier in Saccharomyces cerevisiae. Biochemical Journal, 374, 607-611. http://dx.doi.org/10.1042/BJ20030995
|
[20]
|
Todisco, S., Agrimi, G., Castegna, A. and Palmieri, F. (2006) Identification of the Mitochondrial NAD+ Transporter in Saccharomyces cerevisiae. Journal of Biological Chemistry, 281, 1524-1531.
http://dx.doi.org/10.1074/jbc.M510425200
|
[21]
|
Da Cruz, S., Xenarios, I., Langridge, J., Vilbois, F., Parone, P.A. and Martinou, J.C. (2003) Proteomic Analysis of the Mouse Liver Mitochondrial Inner Membrane. Journal of Biological Chemistry, 278, 41566-41571.
http://dx.doi.org/10.1074/jbc.M304940200
|
[22]
|
Halestrap, A.P. (2012) The Mitochondrial Pyruvate Carrier: Has It Been Unearthed at Last? Cell Metabolism, 16, 141-143. http://dx.doi.org/10.1016/j.cmet.2012.07.013
|
[23]
|
Li, C.L., Wang, M., Ma, X.Y. and Zhang, W. (2014) NRGA1, a Putative Mitochondrial Pyruvate Carrier, Mediates ABA Regulation of Guard Cell Ion Channels and Drought Stress Responses in Arabidopsis. Molecular Plant, 7, 1508-1521. http://dx.doi.org/10.1093/mp/ssu061
|
[24]
|
Lehmann, J.M., Moore, L.B., Smith-Oliver, T.A., Wilkison, W.O., Willson, T.M. and Kliewer, S.A. (1995) An Antidiabetic Thiazolidinedione Is a High Affinity Ligand for Peroxisome Proliferator-Activated Receptor γ (PPARγ). Journal of Biological Chemistry, 270, 12953-12956. http://dx.doi.org/10.1074/jbc.270.22.12953
|
[25]
|
Divakaruni, A.S., Wiley, S.E., Rogers, G.W., Andreyev, A.Y., Petrosyan, S., Loviscach, M., Wall, E.A., Yadava, N., Heuck, A.P., Ferrick, D.A., Henry, R.R., McDonald, W.G., Colca, J.R., Simon, M.I., Ciaraldi, T.P. and Murphy, A.N. (2013) Thiazolidinediones Are Acute, Specific Inhibitors of the Mitochondrial Pyruvate Carrier. Proceedings of the National Academy of Sciences of the United States of America, 110, 5422-5427.
http://dx.doi.org/10.1073/pnas.1303360110
|
[26]
|
Hardie, D.G. (2014) AMPK: Positive and Negative Regulation, and Its Role in Whole-Body Energy Homeostasis. Current Opinion in Cell Biology, 33C, 1-7.
|
[27]
|
Colca, J.R., McDonald, W.G., Cavey, G.S., Cole, S.L., Holewa, D.D., Brightwell-Conrad, A.S., Wolfe, C.L., Wheeler, J.S., Coulter, K.R., Kilkuskie, P.M., Gracheva, E., Korshunova, Y., Trusgnich, M., Karr, R., Wiley, S.E., Divakaruni, A.S., Murphy, A.N., Vigueira, P.A., Finck, B.N. and Kletzien, R.F. (2013) Identification of a Mitochondrial Target of Thiazolidinedione Insulin Sensitizers (mTOT)—Relationship to Newly Identified Mitochondrial Pyruvate Carrier Proteins. PLoS ONE, 8, e61551. http://dx.doi.org/10.1371/journal.pone.0061551
|
[28]
|
Vigueira, P.A., McCommis, K.S., Schweitzer, G.G., Remedi, M.S., Chambers, K.T., Fu, X., McDonald, W.G., Cole, S.L., Colca, J.R., Kletzien, R.F., Burgess, S.C. and Finck, B.N. (2014) Mitochondrial Pyruvate Carrier 2 Hypomorphism in Mice Leads to Defects in Glucose-Stimulated Insulin Secretion. Cell Reports, 7, 2042-2053.
http://dx.doi.org/10.1016/j.celrep.2014.05.017
|
[29]
|
Vacanti, N.M., Divakaruni, A.S., Green, C.R., Parker, S.J., Henry, R.R., Ciaraldi, T.P., Murphy, A.N. and Metallo, C.M. (2014) Regulation of Substrate Utilization by the Mitochondrial Pyruvate Carrier. Molecular Cell, 56, 425-435.
http://dx.doi.org/10.1016/j.molcel.2014.09.024
|
[30]
|
Yang, C., Sudderth, J., Dang, T., Bachoo, R.M., Bachoo, R.G., McDonald, J.G. and DeBerardinis, R.J. (2009) Glioblastoma Cells Require Glutamate Dehydrogenase to Survive Impairments of Glucose Metabolism or Akt Signaling. Cancer Research, 69, 7986-7993. http://dx.doi.org/10.1158/0008-5472.CAN-09-2266
|
[31]
|
Yang, C., Ko, B., Hensley, C.T., Jiang, L., Wasti, A.T., Kim, J., Sudderth, J., Calvaruso, M.A., Lumata, L., Mitsche, M., Rutter, J., Merritt, M.E. and DeBerardinis, R.J. (2014) Glutamine Oxidation Maintains the TCA Cycle and Cell Survival during Impaired Mitochondrial Pyruvate Transport. Molecular Cell, 56, 414-424.
http://dx.doi.org/10.1016/j.molcel.2014.09.025
|
[32]
|
Cairns, R.A., Harris, I.S. and Mak, T.W. (2011) Regulation of Cancer Cell Metabolism. Nature Reviews Cancer, 11, 85-95. http://dx.doi.org/10.1038/nrc2981
|
[33]
|
Schell, J.C., Olson, K.A., Jiang, L., Hawkins, A.J., Van Vranken, J.G., Xie, J., Egnatchik, R.A., Earl, E.G., DeBerardinis, R.J. and Rutter, J. (2014) A Role for the Mitochondrial Pyruvate Carrier as a Repressor of the Warburg Effect and Colon Cancer Cell Growth. Molecular Cell, 56, 400-413. http://dx.doi.org/10.1016/j.molcel.2014.09.026
|
[34]
|
Moreb, J.S. (2008) Aldehyde Dehydrogenase as a Marker for Stem Cells. Current Stem Cell Research & Therapy, 3, 237-246. http://dx.doi.org/10.2174/157488808786734006
|
[35]
|
Tirino, V., Desiderio, V., Paino, F., De Rosa, A., Papaccio, F., La Noce, M., Laino, L., De Francesco, F. and Papaccio, G. (2013) Cancer Stem Cells in Solid Tumors: An Overview and New Approaches for Their Isolation and Characterization. FASEB Journal, 27, 13-24. http://dx.doi.org/10.1096/fj.12-218222
|
[36]
|
Leushacke, M. and Barker, N. (2012) Lgr5 and Lgr6 as Markers to Study Adult Stem Cell Roles in Self-Renewal and Cancer. Oncogene, 31, 3009-3022. http://dx.doi.org/10.1038/onc.2011.479
|
[37]
|
Zhou, J., Ng, S.B. and Chng, W.J. (2013) LIN28/LIN28B: An Emerging Oncogenic Driver in Cancer Stem Cells. International Journal of Biochemistry & Cell Biology, 45, 973-978. http://dx.doi.org/10.1016/j.biocel.2013.02.006
|
[38]
|
Iv Santaliz-Ruiz, L.E., Xie, X., Old, M., Teknos, T.N. and Pan, Q. (2014) Emerging Role of Nanog in Tumorigenesis and Cancer Stem Cells. International Journal of Cancer, 135, 2741-2748. http://dx.doi.org/10.1002/ijc.28690
|